50790-28-8

Basic information

• Product Name: 4-METHYLSULPHONAMINOBENZOIC ACID METHYL ESTER
• Synonyms: 4-METHYLSULPHONAMINOBENZOIC ACID METHYL ESTER;AURORA 2945;Methyl 4-MethanesulfonaMidobenzoate;methyl 4-(methylsulfonamido)benzoate;4-Methanesulfonylamino-benzoic acid methyl ester
• CAS NO: 50790-28-8
• Molecular Formula: C₉H₁₁NO₄S
• Molecular Weight: 229.25
• Mol File: 50790-28-8.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-METHYLSULPHONAMINOBENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLSULPHONAMINOBENZOIC ACID METHYL ESTER(50790-28-8)
• EPA Substance Registry System: 4-METHYLSULPHONAMINOBENZOIC ACID METHYL ESTER(50790-28-8)

Safety Data

• Hazardous Substances Data: 50790-28-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 7151-76-0 4-(methylsulfonamido)benzoic acid 
• 624-90-8 Methanesulfonyl azide 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 3144-09-0 methanesulfonamide 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 124-63-0 methanesulfonyl chloride 
• 619-45-4 4-methoxycarbonyl aniline 

Downstream Products

• 107726-50-1 N-(2-aminoethyl)-4-<(methylsulfonyl)amino>benzamide 
• 163430-53-3 methyl 4-[(3-bromopropyl)methanesulfonylamino]benzoate 
• 93-58-3 benzoic acid methyl ester 
• 135036-55-4 4-[(methyl)(methylsulfonyl)amino]benzoic acid methyl ester 
• 857540-46-6 C₁₃H₁₂N₂O₄S 
• 92526-61-9 N-(4-(hydrazinecarbonyl)phenyl)methanesulfonamide 
• 774238-85-6 N-[4-(hydroxymethyl)phenyl]methanesulfonamide 
• 129895-56-3 N-[(1S,2S)-2-(2-Hydroxy-3-phenoxy-propylamino)-cyclohexyl]-4-methanesulfonylamino-benzamide 
• 129872-39-5 N-{2-[2-Hydroxy-3-(naphthalen-1-yloxy)-propylamino]-ethyl}-4-methanesulfonylamino-benzamide 
• 129872-41-9 N-{2-[3-(2-Cyano-phenoxy)-2-hydroxy-propylamino]-ethyl}-4-methanesulfonylamino-benzamide 
• 129895-55-2 N-{2-[2-Hydroxy-3-(4-methoxy-phenoxy)-propylamino]-ethyl}-4-methanesulfonylamino-benzamide 
• 129872-40-8 N-[2-(2-Hydroxy-3-phenoxy-propylamino)-ethyl]-4-methanesulfonylamino-benzamide 

Relevant articles and documents

SUBSTITUTED INHIBITORS OF MENIN-MLL AND METHODS OF USE

The present disclosure provides methods of inhibiting the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The methods are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL

Mild hypervalent iodine mediated oxidative nitration of N-aryl sulfonamides

An oxidative and acid-free method for the nitration of N-aryl sulfonamides has been developed using a combination of sodium nitrite as cheap and easy to handle NO2-source and the hypervalent iodine reagent PIFA as stoichiometric oxidant. Under

Mild Pd-catalyzed N -arylation of methanesulfonamide and related nucleophiles: Avoiding potentially genotoxic reagents and byproducts

A convenient, general, and high yielding Pd-catalyzed cross-coupling of methanesulfonamide with aryl bromides and chlorides is reported. The use of this method eliminates concern over genotoxic impurities that can arise when an aniline is reacted with methanesulfonyl chloride. The application of this method to the synthesis of dofetilide is also reported.