163526-35-0

Basic information

• Product Name: 1-CYCLOPENTYL-3-METHYL-PIPERAZINE
• Synonyms: 1-CYCLOPENTYL-3-METHYL-PIPERAZINE
• CAS NO: 163526-35-0
• Molecular Formula: C10H20N2
• Molecular Weight: 168.282
• Mol File: 163526-35-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-CYCLOPENTYL-3-METHYL-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYCLOPENTYL-3-METHYL-PIPERAZINE(163526-35-0)
• EPA Substance Registry System: 1-CYCLOPENTYL-3-METHYL-PIPERAZINE(163526-35-0)

Safety Data

• Hazardous Substances Data: 163526-35-0(Hazardous Substances Data)

Usage

Classification

Piperazine derivative

Usage

Pharmaceutical intermediate, building block for drug synthesis

Potential Applications

Treatment of central nervous system disorders, development of new medications for other medical conditions

Importance

Valuable tool for researchers and drug developers in the pharmaceutical industry

Unique Features

Chemical structure and properties

Upstream product

• 137-43-9 Cyclopentyl bromide 
• 109-07-9 (RS)-2-methylpiperazine 

Relevant articles and documents

Synthesis of 1,4-disubstituted-2-methylpiperazines and study of their analgesic properties

A series of N,N-disubstituted-2-methylpiperazines (3a-e) has been synthesized and compounds tested both in vitro and in vivo for their analgesic properties. Binding studies showed that the new compounds are devoid of relevant affinity towards μ receptors. However, compound 3a displayed significant analgesic properties both in the hot plate test and in the mouse phenyl-p-benzoquinone induced abdominal constriction test (MAC), whereas the other derivatives were found active only in MAC test. Moreover, it should be noted that compound 3a elicited a Straub-tail reaction also at the lowest administered dose (10 mg/kg, ip) and this effect was antagonized by naloxone.