16362-97-3Relevant academic research and scientific papers
Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor
Qiao, Chang-Jiang,Ali, Hamed I.,Ahn, Kwang H.,Kolluru, Srikanth,Kendall, Debra A.,Lu, Dai
, p. 517 - 529 (2016)
5-Chloro-3-ethyl-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide (ORG27569, 1) is a prototypical allosteric modulator for the cannabinoid CB1 receptor. Based on this indole-2-carboxamide scaffold, we designed and synthesized novel CB1 allosteric m
Synthesis of photoreactive 2-phenethylamine derivatives-synthesis of adenosine derivatives enabling functional analysis of adenosine receptors by photoaffinity labeling
Murai, Yuta,Masuda, Katsuyoshi,Ogasawara, Yui,Wang, Lei,Hashidoko, Yasuyuki,Hatanaka, Yasumaru,Iwata, So,Kobayashi, Takuya,Hashimoto, Makoto
, p. 2428 - 2433 (2013/05/22)
2-Phenylethylamine is well known as a substructure of many biologically active compounds, and the synthesis of its photoreactive derivatives to allow the analysis of biological functions is reported. This allowed us to synthesise ligands for adenosine rec
TRIAZOLE COMPOUNDS AND THE THERAPEUTIC USE THEREOF
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Page/Page column 35, (2008/06/13)
The invention relates to triazole compounds of general formula (I), wherein A, B, R1, R2, R3 and R4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound of general formula (I) in addition to the use of the compound (I) for producing a pharmaceutical agent for treating illnesses, responding to the effects of dopamine-D3-receptor antagonists or dopamine-D3-receptor agonists, especially for treating disorders in the central nervous system.
Radiation-curable compositions containing photoinitiators linked by a covalent bond
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, (2008/06/13)
A process for the preparation of a radiation-curable acrylate composition, wherein to compounds A containing at least 2 acrylic groups there are added benzophenone derivatives which are not copolymerizable by free-radical copolymerization and which contain at least one primary or secondary amino group or a hydroxyl group or a mercapto group.
