163671-11-2

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 163671-10-1 9-fluorenylmethyloxycarbonyl-5-(4,4'dimethoxytrityloxy)methyl-3-hydroxypyrrolidine 
• 163671-09-8 N-Fmoc-3R-hydroxypyrrolidine-5S-methanol 
• 88050-17-3 N-Fmoc-trans-4-Hydroxy-L-Proline 
• 65-85-0 benzoic acid 
• 151953-64-9 (3R,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}pyrrolidine-3-ol 

Downstream Products

• 163671-22-5 Diisopropyl-phosphoramidous acid (3R,5S)-1-benzoyl-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-pyrrolidin-3-yl ester 2-cyano-ethyl ester 

Relevant academic research and scientific papers

Synthesis of N-substituted hydroxyprolinol phosphoramidites for the preparation of combinatorial libraries

A series of N-substituted DMT-hydroxymethylpyrrolidinol phosphoramidites has been prepared from trans-4-hydroxyproline. These can be coupled in high yield and purity using automated synthesis techniques, allowing a wide range of functionalities to be intr