163726-70-3Relevant academic research and scientific papers
HETEROARYL AMINES AS NOVEL ACETYLCHOLINESTERASE INHIBITORS
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, (2008/06/13)
Compounds of the formula wherein ring A, ring B, ring D, R2, R3, R.4, R5, R.6, R11, R12, R13, E, G, X and P are as defined below. The compounds of formula I are cholinesterase inhibitors and are useful in enhancing memory in patients suffering from dementia and Alzheimer's disease
Design and Synthesis of 1-Heteroaryl-3-(1-benzyl-4-piperidinyl)propan-1-one Derivatives as Potent, Selective Acetylcholinesterase Inhibitors
Nagel, Arthur A.,Liston, Dane R.,Jung, Stanley,Mahar, Melissa,Vincent, Lawrence A.,et al.
, p. 1084 - 1089 (2007/10/02)
Herein is described the synthesis and structure-activity relationship of a novel series of aromatic and heteroaromatic 3-(1-benzyl-4-piperidinyl)propan-1-one derivatives that display potent and selective inhibition of the enzyme acetylcholinesterase (AChE
