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163759-94-2

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  • Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

    Cas No: 163759-94-2

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  • Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

    Cas No: 163759-94-2

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163759-94-2 Usage

Uses

N4-Benzoyl-5''-O-DMT-2''-O-methylcytidine 3''-CE phosphoramidite (CAS# 163759-94-2) is a nucleotide used in the stereoselective synthesis of nucleoside alkyl-phosphonates.

Check Digit Verification of cas no

The CAS Registry Mumber 163759-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,7,5 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 163759-94:
(8*1)+(7*6)+(6*3)+(5*7)+(4*5)+(3*9)+(2*9)+(1*4)=172
172 % 10 = 2
So 163759-94-2 is a valid CAS Registry Number.

163759-94-2Downstream Products

163759-94-2Relevant articles and documents

METHODS FOR THE PREVENTION AND TREATMENT OF MAJOR ADVERSE CARDIOVASCULAR EVENTS USING COMPOUNDS THAT MODULATE APOLIPOPROTEIN B

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Paragraph 00646, (2016/03/22)

Provided herein, for example, are methods generally relating to preventing, treating and/or managing a major adverse cardiovascular event in a subject with a disease or condition at risk for a major adverse cardiovascular event, e.g., familial hypercholesterolemia. Also provided herein are methods relating to administering to the patient a therapeutically effective amount of an antisense oligonucleotide having a nucleobase SEQ ID NO: 247 (e.g., mipomersen).

Modulation of DC-SIGN expression

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Page/Page column 12, (2008/06/13)

Compounds, compositions and methods are provided for modulating the expression of DC-SIGN. The compositions comprise oligonucleotides, targeted to nucleic acid encoding DC-SIGN. Methods of using these compounds for modulation of DC-SIGN expression and for diagnosis and treatment of diseases and conditions associated with expression of DC-SIGN are provided.

Antisense inhibition via RNAse H-independent reduction in mRNA

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Page/Page column 20, (2010/02/12)

The present invention provides compositions and methods for reducing levels of a preselected mRNA, using antisense compounds targeted to a splice site or a region up to 50 nucleobases upstream of an exon/intron junction on said mRNA. Preferably, said antisense compounds do not elicit RNAse H cleavage of the mRNA.

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