16377-62-1 Usage
Description
Ethyl 6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate is a chemical compound with the molecular formula C14H12FNO3. It is a derivative of quinoline, a heterocyclic compound with a six-membered ring structure containing nitrogen and carbon atoms. Ethyl 6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate is structurally similar to the anti-malarial drug chloroquine and has potential pharmaceutical applications. The ethyl ester group in the compound enhances its solubility in organic solvents and its potential for use in drug formulations. The presence of the fluorine atom in the molecule may confer specific properties or biological activities to the compound, although further research and testing are required to fully understand its potential uses and effects.
Uses
Used in Pharmaceutical Industry:
Ethyl 6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate is used as a potential pharmaceutical agent for its structural similarity to the anti-malarial drug chloroquine. Its potential applications may include the development of new drugs for the treatment of malaria or other diseases, given its unique molecular structure and properties.
Used in Drug Formulation:
Ethyl 6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate is used as a component in drug formulations due to its enhanced solubility in organic solvents, which can improve the bioavailability and efficacy of the drug. The ethyl ester group in the compound contributes to its increased solubility, making it a valuable candidate for the development of new drug formulations.
Used in Medicinal Chemistry Research:
Ethyl 6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate is used as a research compound in medicinal chemistry to explore its potential biological activities and properties. The presence of the fluorine atom in the molecule may provide unique characteristics that can be harnessed for the development of new therapeutic agents. Further research is needed to fully understand the compound's potential and its effects on various biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 16377-62-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,7 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16377-62:
(7*1)+(6*6)+(5*3)+(4*7)+(3*7)+(2*6)+(1*2)=121
121 % 10 = 1
So 16377-62-1 is a valid CAS Registry Number.
16377-62-1Relevant articles and documents
Facile synthesis of 4-quinolone derivatives via one-pot cascade reaction under transition-metal-free conditions
Huang, Chao,Guo, Jia-Hui,Fu, Huang-Mei,Yuan, Ming-Long,Yang, Li-Juan
supporting information, p. 3777 - 3781 (2015/06/08)
A practical and efficient strategy has been described for the preparation of 4-quinolone derivatives. Using commercially available diethyl acetylenedicarboxylate and aromatic amines as starting materials, the synthetic protocol has been achieved and affor
