1638101-76-4Relevant academic research and scientific papers
C-H oxygenation and N-trifluoroacylation of arylamines under metal-free conditions: A convenient approach to 2-aminophenols and N-trifluoroacyl-ortho- aminophenols
Venkateswarlu, Vunnam,Kumar, K. A. Aravinda,Balgotra, Shilpi,Reddy, G. Lakshma,Srinivas,Vishwakarma, Ram A.,Sawant, Sanghapal D.
, p. 6641 - 6645 (2014)
Direct ortho-hydroxylation through C-H oxygenation and N-trifluoroacylation of anilines was achieved in a single step under metal-free conditions by using a combination of TFA and oxone. The method allowed the formation of functionalised amino phenolic compounds such as ortho-hydroxy-N- trifluoroacetanilides in good yields with broad substrate scope.
