163812-44-0Relevant articles and documents
A highly convergent approach toward (-)-brevenal
Crimmins, Michael T.,Shamszad, Mariam,Mattson, Anita E.
supporting information; experimental part, p. 2614 - 2617 (2010/08/22)
Progress toward a highly convergent, asymmetric synthesis of brevenal is reported. Construction of the AB-ring and E-ring cyclic ether fragments was achieved through asymmetric alkylation/ring-closing metathesis strategies. A Horner-Wadsworth-Emmons olefination was used in a key bond-forming step to couple the advanced cyclic fragments and enable rapid access to the AB-E ring system.
