1638138-06-3

Upstream product

• 1638138-05-2 (3,4-dimethoxyphenyl)((R)-2,2-cyclohexylidene-1,3-dioxolan-4-yl)methanol 

Downstream Products

• 1638138-09-6 (2R,3R)-3-(4-methoxybenzyloxy)-3-(3,4-dimethoxyphenyl)propane-1,2-diol 
• 1638138-10-9 (2R,3R)-3-(4-methoxybenzyloxy)-2-hydroxy-3-(3,4-dimethoxyphenyl)propyl 4-methylbenzenesulphonate 
• 1638138-11-0 (1R,2R)-1-(4-methoxybenzyloxy)-1-(3,4-dimethoxyphenyl)propan-2-ol 
• 1638138-07-4 (R)-(3,4-dimethoxyphenyl)((R)-2,2-cyclohexylidene-1,3-dioxolan-4-yl)methanol 

Relevant academic research and scientific papers

Titanocene(III) chloride mediated radical induced addition-elimination route to the synthesis of racemic and optically active trisubstituted tetrahydrofurans: Formal synthesis of magnofargesin and 7’-epimagnofargesin

Titanocene(III) Chloride mediated radical induced synthesis of 4-benzylidene substituted tetrahydrofuran, a typical lignan skeleton, has been accomplished in good yield through addition-elimination route in racemic as well as in optically active forms. The method has been applied to the synthesis of furano lignans, magnofargesin (1) and 7’-epimagnofargesin (2) in optically active forms.

A concise and simple synthesis of 1-hydroxy-phenethylamine derivatives: Formal synthesis of naturally occurring norephedrine, virolin and 3-hydroxy-2-phosphonylmethoxypropyl adenine

A concise and simple synthesis of 1-hydroxy-phenethylamine derivatives has been achieved following classical organic transformations using commercially available chiral pools. The said derivatives were explored for the synthesis of naturally occurring bio-active small molecules. Formal synthesis of norephedrine, virolin and 3-hydroxy-2-phosphonylmethoxypropyl adenine has been demonstrated.