1638641-75-4Relevant academic research and scientific papers
Synthesis of some new pyrazole, pyrimidine, pyridazine, and their fused derivatives from 3-oxo-3,n-diphenylpropionamide
Abdelrazek, Fathy M.,Elkholy, Yehia M.,Salah, Ali M.,Abdelazeem, Nagwa M.,Metz, Peter
, p. 824 - 829 (2014/06/10)
The title compounds were obtained from the reactions of 3-oxo-3,N-diphenylpropionamide 3 with dimethylformamide dimethylacetal followed by hydrazine to afford the pyrazole 7, condensation with benzaldehyde followed by cyclocondensation with guanidine to afford the pyrimidine derivative 13, condensation with active methylenes followed by azo coupling of the products followed by cyclization to afford the pyridazines 17a, 17b. The pyridazinone 17b was explored for the synthesis of some novel pyridazine-fused heterocyclic compounds 19, 21, 24a, 24b, 24c, and 26. All structures were proved via their elemental analyses and spectral data.
