1638642-70-2Relevant articles and documents
Pd/C-catalyzed synthesis of isoquinolones through C-H Activation
Shu, Zhen,Li, Wei,Wang, Baiquan
, p. 605 - 608 (2015)
The direct synthesis of isoquinolones from benzamides and alkynes through C-H activation was developed by using Pd/C as a heterogeneous catalyst without a ligand under mild conditions. A variety of isoquinolones were obtained in good yields with excellent regioselectivities. The Pd/C catalyst could be recycled three times without a significant decrease in the activity (yields as high as 85). Activation complete: The direct synthesis of isoquinolones from benzamides and alkynes through C-H activation is developed by using Pd/C as a heterogeneous catalyst. The Pd/C catalyst can be recycled three times without a significant decrease in the activity.
Organocatalytic oxidative annulation of benzamide derivatives with alkynes
Manna, Srimanta,Antonchick, Andrey P.
supporting information, p. 7324 - 7327 (2014/07/21)
Organocatalytic annulation by functionalization of benzamide derivatives with alkynes has been developed. We report a new approach of cycloaddition under mild reaction conditions using simple catalysts, such as iodobenzene and peracetic acid, as oxidant. Those novel, mild reaction conditions provided a straightforward synthesis of isoquinolones with fast reaction rate. Notable selectivity in annulation of unsymmetrically disubstituted alkynes was demonstrated.
