1638643-69-2Relevant academic research and scientific papers
Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol
Zhu, Lei,Ren, Xiaojian,Yu, Yinghua,Ou, Pengcheng,Wang, Zhi-Xiang,Huang, Xueliang
supporting information, p. 2087 - 2092 (2020/03/04)
A ligand-controlled palladium-catalyzed three-component reaction of o-bromobenzaldehyde, N-tosylhydrazone, and methanol is described. This reaction uses readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility.
Synthesis of N,N-disubstituted 1-aryl-1,3-dihydro-2H-isoindole-2-carbothioamides
Kobayashi, Kazuhiro,Shigemura, Yuuho,Tanmatsu, Miyuki
, p. 844 - 856 (2016/07/06)
A convenient method for the synthesis of N,N-disubstituted 1-aryl-1,3-dihydro-2H-isoindole-2-carbothioamides starting from 2-[aryl(methoxy)methyl]phenyl bromides is described. Thus, the reaction of 1-[aryl(methoxy)methyl]-2-(isothiocyanatomethyl)benzenes, derived from the starting materials by an easily operated five-step sequence under mild conditions, with secondary amines provides the corresponding thiourea derivatives, which cyclize on treatment with methanesulfonic acid to afford the desired products.
Synthesis of substituted biaryls through gold-catalyzed petasis-ferrier rearrangement of propargyl ethers
Pati, Kamalkishore,Alabugin, Igor V.
supporting information, p. 3986 - 3990 (2014/07/08)
Au-catalyzed cycloisomerization of aryl propargyl ethers provides controlled transition from alkyne to carbonyl chemistry followed up by a Petasis-Ferrier rearrangement/aromatization cascade leading to substituted biaryls with functionalized naphthalene cores. An Au-catalyzed sequence of alkoxy group translocation, Petasis-Ferrier rearrangement, and aromatization transforms aryl propargyl ethers into substituted biaryls with functionalized naphthalene cores. Copyright
