16388-07-1 Usage
General Description
(2E)-2-(5-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)-1,1-dimethylhydrazine, also known as Dimebon, is an experimental drug that has been investigated for its potential use in the treatment of Alzheimer's disease and other neurodegenerative disorders. It is a derivative of the antihistamine drug dimebolin, and has been found to have neuroprotective and cognitive-enhancing effects in some studies. However, further research is needed to determine its safety and efficacy for these uses. The chemical's structure includes a dimethylhydrazine group, which is known for its potential carcinogenic and toxic effects, and the methoxy group, which is commonly found in drugs and natural compounds and can contribute to their pharmacological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 16388-07-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,8 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16388-07:
(7*1)+(6*6)+(5*3)+(4*8)+(3*8)+(2*0)+(1*7)=121
121 % 10 = 1
So 16388-07-1 is a valid CAS Registry Number.
16388-07-1Relevant articles and documents
TRICYCLIC PYRROLE DERIVATIVES USEFUL AS 5-HT SELECTIVE AGENTS
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, (2008/06/13)
The invention relates to tricyclic pyrrole derivatives useful as 5-HT selective agents of the formula STR1 wherein R 1 to R 4 are, independently, hydrogen, halogen, lower alkyl, phenyl, cycloalkyl or lower alkoxy and R 2 additionally is lower alkoxycarbonyl, acyloxy or mesyloxy;R 5 to R 7 are, independently, hydrogen or lower alkyl;X is--CH 2 CH(C 6 H. sub.5)--,--CH=C(C 6 H 5)--,--YCH 2--,--CH=CH--or--(CR 11 R 12) n ;R 11 and R 12 are, independently, hydrogen, phenyl, lower alkyl or halogen;n is 1 to 3 andy is O or S,as well as pharmaceutically acceptable salts of basic compounds of formula I with pharmaceutically acceptable acids.
