1639236-91-1

Upstream product

• 137-43-9 Cyclopentyl bromide 
• 57179-35-8 3-hydroxy-5-methoxybenzaldehyde 
• 4392-24-9 Cinnamyl bromide 
• 812646-64-3 5-hydroxy-4-methoxy-2-[(1E)-3-phenyl-2-propenyl]benzaldehyde 
• 621-59-0 isovanillin 

Relevant academic research and scientific papers

MCPBA-Mediated Intramolecular Oxidative Annulation of ortho-Crotyl or Cinnamyl Arylaldehydes: Synthesis of Benzofused Five-, Six-, and Seven-Membered Oxacycles

mCPBA-mediated intramolecular oxidative annulation of ortho-crotyl or cinnamyl arylaldehydes provides chroman, coumaran, isochroman, and tetrahydrobenzo[c]oxepine under different reaction conditions. This research investigates the reaction conditions for facile and efficient transformation.

Synthesis of 2-hydroxymethyl-2,3-dihydrobenzofurans

A one-pot protocol toward 2-hydroxymethyl-2,3-dihydrobenzofurans (1) starting with oxygenated o-allylbenzaldehydes (3) was described. The facile one-pot process was carried out by the oxidation of o-allylbenzaldehydes (3) with Oxone in the co-solvent of acetone and DMF in the presence of aqueous EDTA solution and then intramolecular ring-closure of the resulting o-allylphenols (2) in acceptable yields.