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Usage

Uses

Used in Pharmaceutical Synthesis:
2-(4-(Methylsulfinyl)butyl)isoindoline-1,3-dione is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form various derivatives. Its versatile reactivity allows for the creation of a wide range of compounds with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-(4-(Methylsulfinyl)butyl)isoindoline-1,3-dione is utilized as a building block for the development of new agrochemicals. Its potential to form diverse derivatives makes it a valuable component in the creation of effective and novel products for agricultural use.
Used in Medicinal Chemistry Research:
2-(4-(Methylsulfinyl)butyl)isoindoline-1,3-dione is employed as a research tool in medicinal chemistry to explore its therapeutic potential in various diseases. Its unique structure and reactivity provide opportunities for the discovery of new drugs and bioactive compounds with significant medical applications.

InChI:InChI=1/C13H15NO3S/c1-18(17)9-5-4-8-14-12(15)10-6-2-3-7-11(10)13(14)16/h2-3,6-7H,4-5,8-9H2,1H3

Upstream product

• 52096-68-1 2-<2-(Methylthio)butyl>-1H-isoindole-1,3(2H)-dione 
• 64-19-7 acetic acid 
• 5394-18-3 2-(4-bromobutyl)isoindoline-1,3-dione 
• 136918-14-4 phthalimide 

Downstream Products

• 4478-93-7 D,L-sulforaphane 
• 550-44-7 N-methylphthalimide 
• 84104-30-3 (+/-)-1-amino-4-(methylsulfinyl)butane 

Relevant academic research and scientific papers

Antioxidant activity of two edible isothiocyanates: Sulforaphane and erucin is due to their thermal decomposition to sulfenic acids and methylsulfinyl radicals

Sulforaphane (SFN) and erucin (ERN) are isothiocyanates (ITCs) bearing, respectively, methylsulfinyl and methylsulfanyl groups. Their chemopreventive and anticancer activity is attributed to ability to modulate cellular redox status due to induction of Phase 2 cytoprotective enzymes (indirect antioxidant action) but many attempts to connect the bioactivity of ITCs with their radical trapping activity failed. Both ITCs are evolved from their glucosinolates during food processing of Cruciferous vegetables, therefore, we studied antioxidant behaviour of SFN/ERN at elevated temperature in two lipid systems. Neither ERN nor SFN inhibit the oxidation of bulk linolenic acid (below 100 °C) but both ITCs increase oxidative stability of soy lecithin (above 150 °C). On the basis of GC-MS analysis we verified our preliminary hypothesis (Antioxidants 2020, 9, 1090) about participation of sulfenic acids and methylsulfinyl radicals as radical trapping agents responsible for the antioxidant effect of edible ITCs during thermal oxidation of lipids at elevated temperatures (above 140 °C).

Cancer chemopreventive activity of sulforamate derivatives

Chemoprevention can be defined as an intervention in the carcinogenic process by use of natural or synthetic substances. Induction of Phase II enzyme is an important mechanism of chemoprevention. In the present studies we have synthesized several derivati

Stabilized sulforaphane

A method of stabilizing sulforaphane is provided. The method includes contacting sulforaphane, or an analog thereof, and a cyclodextrin to form a complex between the sulforaphane, or analog thereof, and the cyclodextrin.