163978-39-0Relevant articles and documents
Noncovalent catalysis of glucose-containing imidazolium salt in solvent-free one-pot synthesis of Ortho-aminocarbonitriles
Zhang, Li-Zhuo,Wan, Yu,Zhang, Xiao-Xiao,Cui, Hao,Zou, Huan,Zhou, Qiu-Ju,Wu, Hui
, p. 4934 - 4937 (2015)
Abstract A glucose-containing imidazolium salt β-1-imidazole-2,3,4,6-tetraacetyl-D-glucopyranosyl bromide was firstly used as efficient noncovalent organocatalyst to promote the solvent-free preparation of ortho-aminocarbonitriles via a four-component con
Synthesis of cobalt tetra-2,3-pyridiniumporphyrazinato with sulfonic acid tags as an efficient catalyst and its application for the synthesis of bicyclic: Ortho -aminocarbonitriles, cyclohexa-1,3-dienamines and 2-amino-3-cyanopyridines
Baghery, Saeed,Dashteh, Mohammad,Khazaei, Ardeshir,Makhdoomi, Sajjad,Safaiee, Maliheh,Yarie, Meysam,Zolfigol, Mohammad Ali
, p. 27824 - 27834 (2020/08/17)
Cobalt tetra-2,3-pyridiniumporphyrazinato with sulfonic acid tag [Co(TPPASO3H)]Cl was produced and catalyzed the synthesis of ortho-aminocarbonitriles, cyclohexa-1,3-dienamines and 2-amino-3-cyanopyridines. The synthesis of 2-amino-3-cyanopyridines by usi
A task-specific biodegradable ionic liquid: a novel catalyst for synthesis of bicyclic ortho-aminocarbonitriles
Gaikwad,Undale,Patil,Patravale,Kamble
, p. 1175 - 1180 (2018/05/22)
Abstract: Herein, we report a novel method for synthesis of bicyclic ortho-aminocarbonitriles catalyzed by biodegradable ionic liquid. The biodegradability (BOD analysis) of all the ionic liquids that are used to carry out the reaction is studied, and the
Multicomponent domino reactions in deep eutectic solvent: An efficient strategy to synthesize multisubstituted cyclohexa-1,3-dienamines
Azizi, Najmedin,Ahooie, Tahereh Soleymani,Hashemi, Mohammad Mahmoudi
, p. 221 - 224 (2017/09/28)
The multicomponent domino reactions of ketones, aldehydes and malononitrile in a deep eutectic solvent (DES) were developed. Urea-choline chloride based DES is effective dual solvents/organocatalysts and affording a series of multisubstituted cyclohexa-1,
DABCO functionalized dicationic ionic liquid (DDIL): A novel green benchmark in multicomponent synthesis of heterocyclic scaffolds under sustainable reaction conditions
Lohar, Trushant,Kumbhar, Arjun,Barge, Madhuri,Salunkhe, Rajshri
, p. 1102 - 1108 (2016/11/09)
A novel DABCO functionalized dicationic ionic liquid (DDIL) has been synthesized using diazabicyclo[2,2,2]octane (DABCO), 1,3-dichloro-2-propanol and NaBF4 in acetonitrile. The IL was fully characterized by IR, NMR and mass spectroscopic techniques. The presence of BF4? anion in IL was confirmed by 19F NMR and also supported by mass analysis. The TGA analysis showed that the IL is thermally stable up to 180?°C temperature. We demonstrated that the presence of the tertiary nitrogen sites and hydroxyl group in the DDIL network enhances the overall activity of DDIL. These make them compatible for base catalyzed one pot multicomponent synthesis of ortho-amino carbonitriles and 3-methyl-4-arylmethylene-isoxazol-5(4H)-ones under grinding without solvent. In addition the activity of DDIL was also studied for synthesis of tetrahydrobenzo[b]pyrans under ultrasound irradiation in water. Furthermore the DDIL was easily recoverable and recyclable many times with modest decrease in activity.
Borax catalyzed domino reactions: Synthesis of highly functionalised pyridines, dienes, anilines and dihydropyrano[3,2-c]chromenes
Molla, Aniruddha,Hussain, Sahid
, p. 29750 - 29758 (2014/08/05)
Borax, an innocuous, inexpensive, and a naturally occurring material, very efficiently catalyzes the Knoevenagel condensation and Michael addition in domino fashion for the construction of highly functionalised pyridines, dienes, anilines and dihydropyran
Novel [4 + 2] cycloaddition reaction of aryl-methylidenemalononitriles to unsaturated chalcogen amides. Synthesis, structure, and properties of triethylammonium 3,5,5-tricyano-1,4,5,6-tetrahydropyridine-2-selenolates and -thiolates
Frolov,Dotsenko,Krivokolysko,Kostyrko
, p. 1289 - 1300 (2014/01/17)
Reaction of arylmethylidenemalononitriles with 3-aryl-2-cyanoprop-2- eneselenoamides in the presence of Et3N gave triethylammonium 4,6-diaryl-3,5,5-tricyano-1,4,5,6-tetrahydropyridine-2-selenolates. A similar reaction with cyclohexylidenecyanothioacetamide yields triethylammonium 4-aryl-1,5,5-tri-cyano-3-azaspiro[5.5]undec-1-ene-2-thiolate. Alkylation of the obtained selenolates and thiolates gives 6-(alkylseleno)-2,4-diaryl-1,4- dihydropyridine-3,3,5(2H)-tricarbonitriles and 4-(alkylthio)-2-aryl-3-aza- spiro[5.5]undec-4-ene-1,1,5-tricarbonitriles, respectivelly. The structure of 2,4-di(2-furyl)-6-{[2-(4-methylphenyl)-2-oxoethyl]seleno}-1,4-dihydropyridine-3, 3,5(2H)-tricarbonitrile has been confirmed by the X-ray structural analysis.
Ternary Condensation of Aldehydes with Activated Nitriles and Cycloalkanones
Abdel-Latif, Fathy Fahim,Shaker, Rafat Mohamed
, p. 146 - 147 (2007/10/03)
Aromatic aldehydes condense with malononitrile or ethyl cyanoacetate and cycloalkanones in the presence of ammonium acetate to give a variety of carbocyclic and heterocyclic products, including pyridones.