163979-81-5Relevant academic research and scientific papers
Thiol-promoted selective addition of ketones to aldehydes
Parnes, Regev,Narute, Sachin,Pappo, Doron
supporting information, p. 5922 - 5925 (2015/02/19)
A simple and efficient thiol-mediated addition of ketones to aromatic and aliphatic aldehydes is reported. This thermodynamically controlled Pummerer/aldol reaction, which can tolerate both moisture and protic functional groups, provides a direct entry to syn-β-thioketones in high chemo- and regioselectivity. Mechanistic studies revealed that selective transformation of the aldehyde to an electrophilic thionium ion species concurrent with the generation of a nucleophilic vinyl sulfide coupling partner from the ketone is imposing cross-coupling over dimerization.
The synthesis of α-acetoxy sulfides and their Lewis acid-mediated reactions
Kraus, George A.
, p. 2599 - 2602 (2007/10/02)
α-Acetoxy sulfides can be conveniently prepared by the reaction of dithioacetals with mercuric acetate at ambient temperature. They react with allyltrimethylsilane, enol silyl ethers, and cyanotrimethylsilane in the presence of SnCl4 to afford
A CONVENIENT METHOD FOR THE PREPARATION OF γ-KETOSULFIDES FROM THIOACETALS
Ohshima, Masahiro,Murakami, Masahiro,Mukaiyama, Teruaki
, p. 1871 - 1874 (2007/10/02)
In the presence of trityl tetrafluoroborate, silyl enol ethers react with thioacetals to give the corresponding γ-ketosulfides in good yields with high stereoselectivity.In a similar manner, γ-ketosulfides are obtained in good yields by the one pot reacti
