1639810-06-2

Basic information

• Product Name: (E)-diethyl (3-(1-(benzyloxy)-3-phenylureido)prop-1-en-1-yl)phosphonate
• Synonyms: (E)-diethyl (3-(1-(benzyloxy)-3-phenylureido)prop-1-en-1-yl)phosphonate
• CAS NO: 1639810-06-2
• Molecular Weight: 418.43
• Mol File: 1639810-06-2.mol

Chemical Properties

• CAS DataBase Reference: (E)-diethyl (3-(1-(benzyloxy)-3-phenylureido)prop-1-en-1-yl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-diethyl (3-(1-(benzyloxy)-3-phenylureido)prop-1-en-1-yl)phosphonate(1639810-06-2)
• EPA Substance Registry System: (E)-diethyl (3-(1-(benzyloxy)-3-phenylureido)prop-1-en-1-yl)phosphonate(1639810-06-2)

Safety Data

• Hazardous Substances Data: 1639810-06-2(Hazardous Substances Data)

Upstream product

• 1639810-56-2 diethyl (E)-(3-((benzyloxy)amino)prop-1-en-1-yl)phosphonate 
• 103-71-9 phenyl isocyanate 
• 622-33-3 N-benzyloxyamine 

Downstream Products

• 1642790-70-2 (+/-)-diethyl ((1-(benzyloxy)-3-phenyl-2-oxoimidazolidin-4-yl)-methyl)phosphonate 
• 1642790-73-5 (+/-)-diethyl ((1-hydroxy-3-phenyl-2-oxoimidazolidin-4-yl)-methyl)phosphonate 
• 1642790-75-7 (+/-)-(1-hydroxy-3-phenyl-2-oxoimidazolidin-4-yl)methylphosphonic acid 

Relevant articles and documents

Fosmidomycin analogues with N-hydroxyimidazole and N-hydroxyimidazolone as a chelating unit

Fosmidomycin has been reported to have many biological activities as an antibacterial and antimalarial, along with being a herbicidal agent. Its unique mode of action involves the inhibition of a key step of the non mevalonate pathway by blockade of a crucial enzyme, the 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), whose expression is present in bacteria, plasmodium parasites and higher plants, but not in mammals. Herein we report the development of fosmidomycin and of FR-900098 constrained analogues belonging to an unusual heterocyclic based complexing subunit involving N-hydroxyimidazoles and cyclic N-hydroxyureas.