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methyl 3-[(tert-butoxycarbonyl)amino]-5-(3-(trimethylsilyl)prop-2-yn-1-yl)benzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1639866-75-3

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1639866-75-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1639866-75-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,9,8,6 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1639866-75:
(9*1)+(8*6)+(7*3)+(6*9)+(5*8)+(4*6)+(3*6)+(2*7)+(1*5)=233
233 % 10 = 3
So 1639866-75-3 is a valid CAS Registry Number.

1639866-75-3Relevant academic research and scientific papers

Preparation of new alkyne-modified ansamitocins by mutasynthesis

Harmrolfs, Kirsten,Mancuso, Lena,Drung, Binia,Sasse, Florenz,Kirschning, Andreas

, p. 535 - 543 (2014/04/17)

The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a thiol linker by Huisgen-type cycloaddition which can principally be utilized to create tumor targeting conjugates. In bioactivity tests, only those new ansamitocin derivatives showed strong antiproliferative activity that bear an ester side chain at C-3.

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