164021-74-3

Basic information

• Product Name: (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol
• Synonyms: (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol
• CAS NO: 164021-74-3
• Molecular Weight: 429.602
• Mol File: 164021-74-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol(164021-74-3)
• EPA Substance Registry System: (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol(164021-74-3)

Safety Data

• Hazardous Substances Data: 164021-74-3(Hazardous Substances Data)

Upstream product

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 37942-07-7 3,5-di-tert-butyl-2-hydroxybenzaldehyde 

Downstream Products

• 2976-30-9 1-methanesulfonyl-4-nitrobenzene 
• 940-12-5 (R)-methyl 4-nitrophenyl sulfoxide 
• 3112-85-4 methylphenylsulfonate 
• 1193-82-4 (S)-methylphenylsulfoxide 
• 4850-71-9 (R)-methyl phenyl sulfoxide 
• 599-70-2 ethyl phenyl sulfone 
• 51207-25-1 (R)-ethyl phenyl sulfoxide 
• 4170-80-3 (S)-(-)-ethylphenylsulfoxide 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 5056-07-5 (S)-methyl p-tolyl sulfoxide 
• 3185-99-7 Methyl p-tolyl sulfone 
• 3466-32-8 4-bromoohenyl methyl sulfone 
• 28227-62-5 (R)-1-bromo-4-(methylsulfinyl)benzene 
• 145166-15-0 (S)-methyl p-bromophenyl sulfoxide 

Relevant articles and documents

Catalytic Chemo-, Regio-, and Enantioselective Bromochlorination of Allylic Alcohols

Herein we describe a highly chemo-, regio-, and enantioselective bromochlorination reaction of allylic alcohols, employing readily available halogen sources and a simple Schiff base as the chiral catalyst. The application of this interhalogenation reaction to a variety of substrates, the rapid enantioselective synthesis of a bromochlorinated natural product, and preliminary extension of this chemistry to dibromination and dichlorination are reported.

Titanium complexes of chiral amino alcohol derived Schiff bases as efficient catalysts in asymmetric oxidation of prochiral sulfides with hydrogen peroxide as an oxidant

An efficient asymmetric oxidation of prochiral sulfides catalyzed by a series of simple in situ generated complexes based on chiral amino alcohol derived Schiff bases with Ti(Oi-Pr)4 was carried out in presence of cheap and environmentally benign oxidant H2O2 at 0 °C. Prochiral sulfides were converted to respective chiral sulfoxides efficiently (conversion, 93%; up to ee, 98%) with this system in 10 h at 0 °C. The present study demonstrated a significant role of steric influence of the substituent attached on both aryl and alkyl moiety on the enantioselectivity. Kinetic studies of the catalytic reaction showed first order dependence on substrate and catalyst whereas it is zero for the oxidant. Kinetic studies in combination with UV-vis. spectral studies were used to propose a catalytic cycle for the sulfoxidation reaction.