164025-07-4

Basic information

• Product Name: (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester
• Synonyms: (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester;2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-acetic acid methyl ester;methyl 2-(2,5-dioxopyrrol-1-yl)acetate
• CAS NO: 164025-07-4
• Molecular Formula: C₇H₇NO₄
• Molecular Weight: 169.13478
• Mol File: 164025-07-4.mol
• Article Data: 8

Chemical Properties

• Melting Point: 45-48℃ (ethyl acetate ligroine )
• Boiling Point: 286.6±23.0 °C(Predicted)
• Appearance: /
• Density: 1.368±0.06 g/cm3(Predicted)
• PKA: -2.78±0.20(Predicted)
• CAS DataBase Reference: (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester(164025-07-4)
• EPA Substance Registry System: (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester(164025-07-4)

Safety Data

• Hazardous Substances Data: 164025-07-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester" is a methyl ester derivative of (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid. It is a heterocyclic compound with a pyrrole ring and two carbonyl groups, making it a diketone. (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester is commonly used in organic and medicinal chemistry as a building block for the synthesis of various compounds. It is also known for its potential pharmaceutical applications, particularly in the development of new drugs. The methyl ester group allows for easy manipulation and modification of the compound's properties, making it a versatile and valuable chemical in scientific research and drug discovery.

Upstream product

• 541-59-3 maleiimide 
• 96-35-5 glycolic acid methyl ester 
• 108-31-6 maleic anhydride 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 616-34-2 methoxycarbonylmethylamine 
• 54930-24-4 (Z)-4-((carboxymethyl)amino)-4-oxobut-2-enoic acid 
• 70802-41-4 (Z)-N-(3-carboxy-1-oxo-2-propenyl)-glycine methyl ester 
• 25021-08-3 N,N-maleoyl-glycine 
• 74-88-4 methyl iodide 

Downstream Products

• 1384683-56-0 methyl 2-[3-(4-fluorophenyl)-4,6-dioxo-3aH,6aH-pyrrolo[3,4-d][1,2]oxazol-5-yl]acetate 
• 1384683-93-5 ⁽¹⁸⁾F-methyl 2-[3-(4-fluorophenyl)-4,6-dioxo-3aH,6aH-pyrrolo[3,4-d][1,2]oxazol-5-yl]acetate 
• 165035-05-2 methyl endo-2-(3,5-dioxo-4-azatricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-acetate 
• 841260-47-7 (5,6-bis{2-[2-(2-(toluol-4-sulfonyloxy)ethoxy)ethoxy]ethoxy}-1,3-dioxo-1,3-dihydroisoindol-2-yl)acetic acid methyl ester 

Relevant articles and documents

Photochemical Reaction of N,N-Dimethylanilines with N-Substituted Maleimides Utilizing Benzaldehyde as the Photoinitiator

Photoorganocatalysis constitutes a powerful domain of photochemistry and organic synthesis. The scaffold of pyrrolo[3,4-c]quinolinoles exhibits interesting and potent inhibition against various enzymes, making them really promising pharmaceutical targets. Herein, we describe a photochemical methodology for the reaction of N,N-dimethylanilines with N-substituted maleimides, utilizing benzaldehyde as the photoinitiator. A variety of substituted N,N-dimethylanilines and N-substituted maleimides were converted into the corresponding adducts in moderate to high yields.

Structure-reactivity relationships in a recognition mediated [3+2] dipolar cycloaddition reaction

The [3+2] dipolar cycloaddition between an azide and maleimide can be accelerated by a factor of more than 100 simply by attaching complementary recognition sites to the reactive partners. This rate acceleration derives from the formation of a reactive bi

Synthesis and properties of chiral N,N-maleoyl derivatives and Diels-Alder reactions with cyclopentadiene

Maleyl amino acid derivatives were prepared from maleic anhydride and cyclized by reaction with ZnCl2 and hexamethyldisilazane yielding maleoyl derivatives. These derivatives were used as dienophiles in cycloadditions with cyclopentadiene. The