164025-54-1

Basic information

• Product Name: Silane, (1,1-dimethylethyl)[(5-iodopentyl)oxy]diphenyl-
• CAS NO: 164025-54-1
• Molecular Formula: C21H29IOSi
• Molecular Weight: 452.451
• Mol File: 164025-54-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)[(5-iodopentyl)oxy]diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)[(5-iodopentyl)oxy]diphenyl-(164025-54-1)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)[(5-iodopentyl)oxy]diphenyl-(164025-54-1)

Safety Data

• Hazardous Substances Data: 164025-54-1(Hazardous Substances Data)

Upstream product

• 121671-76-9 5-(tert-butyldiphenylsilyloxy)pentan-1-ol 
• 111-29-5 1 ,5-pentanediol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 5259-98-3 5-chloropentan-1-ol 
• 878396-94-2 1-(tert-butyldiphenylsilyl)oxy-5-chloropentane 
• 928657-95-8 5-(tert-butyldiphenylsilyloxy)pentyl methanesulfonate 
• 164025-53-0 4-(t-butyldiphenylsiloxy) pentyl-p-toluene sulfonate 

Downstream Products

• 831223-27-9 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenol 
• 878396-90-8 N,N'-bis-[5-(tert-butyldiphenylsilanyloxy)pentyl]ethane-1,2-diamine 
• 878396-91-9 N,N'-bis-[5-(tert-butyldiphenylsilanyloxy)pentyl]butane-1,4-diamine 
• 831223-28-0 ethyl 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetate 
• 831223-29-1 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid 
• 851616-13-2 cladospolide B 
• 96443-55-9 cladospolide C 
• 912351-97-4 [6-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-hexyloxy]-tert-butyl-diphenyl-silane 
• 912351-96-3 [(E)-6-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-hex-5-enyloxy]-tert-butyl-diphenyl-silane 
• 912352-07-9 Toluene-4-sulfonic acid (R)-7-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-heptyl ester 
• 912351-82-7 [(Z)-6-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hex-5-enyloxy]-tert-butyl-diphenyl-silane 
• 912352-05-7 Benzoic acid (E)-(1R,7R,8R)-8-benzyloxy-7-formyloxy-10-methoxycarbonyl-1-methyl-dec-9-enyl ester 
• 912352-12-6 Benzoic acid (E)-(1S,7R,8R)-8-benzyloxy-7-formyloxy-10-methoxycarbonyl-1-methyl-dec-9-enyl ester 
• 912352-03-5 Benzoic acid (R)-6-((2R,3R,4R,5S)-3-benzyloxy-4,5-dihydroxy-tetrahydro-furan-2-yl)-1-methyl-hexyl ester 

Relevant articles and documents

Copper-Catalyzed Reductive Trifluoromethylation of Alkyl Iodides with Togni's Reagent

This work illustrates a reductive cross-electrophile coupling protocol for trifluoromethylation of alkyl iodides under Cu-catalyzed/Ni-promoted reaction conditions. The use of diboron esters as the terminal reductant allows the effective generation of the alkyl-CF3 products with excellent functional group tolerance and broad substrate scope. A mechanism involving a reaction of alkyl-Cu with Togni's reagent was proposed.

A remarkably useful sulfur bridge as synthetic lever in an approach to Javanicin B

A concise and efficient synthesis of a non-racemic advanced intermediate to the quassinoid javanicin B is disclosed. The strategy is centred on a triple diene-transmissive Diels-Alder cycloaddition to form the four rings of javanicin B. A sulfur bridge plays several crucial roles allowing an intramolecular cycloaddition to occur with complete stereoselectivity, controlling the stereochemical outcome of another cycloaddition, and transforming into a pivotal electrophile for the introduction of a particularly hindered methyl group.

Attempts directed towards the synthesis and determination of the absolute stereochemistry of iso-cladospolide-B and cladospolides-B and C

Attempts to synthesise iso-cladospolide-B, cladospolide-B and cladospolide-C resulted in macrolides 1, 2 and 4 along with butenolide 3. Of the three stereogenic centres, the C-4/C-5 vic-diol was obtained from tartaric acid and d-glucose, while the C-11 st