16403-07-9

Basic information

• Product Name: (2E)-2-ethylpent-2-enoic acid
• Synonyms: 2-pentenoic acid, 2-ethyl-, (2E)-
• CAS NO: 16403-07-9
• Molecular Formula: C₇H₁₂O₂
• Molecular Weight: 128.169
• Mol File: 16403-07-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 225.2°C at 760 mmHg
• Flash Point: 132°C
• Density: 0.97g/cm³
• Vapor Pressure: 0.0319mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: (2E)-2-ethylpent-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-ethylpent-2-enoic acid(16403-07-9)
• EPA Substance Registry System: (2E)-2-ethylpent-2-enoic acid(16403-07-9)

Safety Data

• Hazardous Substances Data: 16403-07-9(Hazardous Substances Data)

Usage

General Description

(2E)-2-ethylpent-2-enoic acid is a chemical compound with the molecular formula C8H14O2. It is an unsaturated carboxylic acid with a double bond in the 2 position and a methyl group attached to the carbon at position 2 of the pentenoyl chain. (2E)-2-ethylpent-2-enoic acid is used in the synthesis of pharmaceuticals and other organic compounds. It is also used as a building block in the production of flavors and fragrances. The presence of the carboxylic acid group makes it an important intermediate in organic synthesis, and its unique structure and properties make it valuable in various chemical processes.

Upstream product

• 928-49-4 hex-3-yne 
• 124-38-9 carbon dioxide 
• 77324-63-1 2-ethyl-3-pentenoic acid 
• 3491-57-4 2-ethyl-pent-2-enal 
• 7732-18-5 water 
• 71718-48-4 methyl (E)-2-ethyl-2-pentenoate 
• 123-38-6 propionaldehyde 
• 533-68-6 2-bromobutyric acid ethyl ester 
• 474672-54-3 ethyl 2-ethylpent-2-enoate 

Relevant articles and documents

Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2: formation of α,β-unsaturated carboxylic acids

Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2 (atmospheric pressure) has been reported. A range of alkynes were transformed to the corresponding α,β-unsaturated carboxylic acids in high yields with high regioselectivity. The reaction proceeded with hydrotitanation, transmetalation, and subsequently carboxylation with CO2

Cp2ZrCl2-mediated three-component coupling reactions of CO2, ethylene (or alkynes), and electrophiles leading to carboxylic acid derivatives

Zirconacycles 1 and 2 can be simply generated from Cp2ZrCl 2, EtMgBr, and an atmospheric pressure of CO2. The treatment of Cp2ZrCl2 with EtMgBr followed by exposure to CO2 generates zirconacycle 1, which can react with various electrophiles to give a variety of carboxylic acid derivatives. Unsaturated zirconacycles 2 can also generated from Cp2ZrCl2, EtMgBr, alkynes, and CO2. Complexes 2 react with electrophiles to give α,β-unsaturated acids stereoselectively.