16403-07-9Relevant articles and documents
Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2: formation of α,β-unsaturated carboxylic acids
Shao, Peng,Wang, Sheng,Du, Gaixia,Xi, Chanjuan
, p. 3534 - 3539 (2017/01/25)
Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2 (atmospheric pressure) has been reported. A range of alkynes were transformed to the corresponding α,β-unsaturated carboxylic acids in high yields with high regioselectivity. The reaction proceeded with hydrotitanation, transmetalation, and subsequently carboxylation with CO2
Cp2ZrCl2-mediated three-component coupling reactions of CO2, ethylene (or alkynes), and electrophiles leading to carboxylic acid derivatives
Yamashita, Kohei,Chatani, Naoto
, p. 919 - 922 (2007/10/03)
Zirconacycles 1 and 2 can be simply generated from Cp2ZrCl 2, EtMgBr, and an atmospheric pressure of CO2. The treatment of Cp2ZrCl2 with EtMgBr followed by exposure to CO2 generates zirconacycle 1, which can react with various electrophiles to give a variety of carboxylic acid derivatives. Unsaturated zirconacycles 2 can also generated from Cp2ZrCl2, EtMgBr, alkynes, and CO2. Complexes 2 react with electrophiles to give α,β-unsaturated acids stereoselectively.