16407-34-4

Upstream product

• 41614-08-8 3-ethyl-2-methylsulfanyl-benzothiazolium; iodide 
• 2801-21-0 benzothiazole sulfenamide 
• 30463-59-3 tetrapropyl-diamidophosphoric acid ethyl ester 
• 2632-88-4 ethyl N,N'-tetraethyldiamidophosphite 
• 10220-34-5 N-isopropyl-2-benzothiazolesulfenamide 
• 95-33-0 N-(cyclohexyl)benzothiazole-2-sulfenamide 
• 26773-69-3 N-(phenylmethyl)-2-benzothiazolesulfenamide 
• 2524-04-1 diethyl phosphorochloridothioate 
• 149-30-4 2-Mercaptobenzothiazole 
• 762-04-9 phosphonic acid diethyl ester 
• 149-30-4 2-thioxo-3H-1,3-benzothiazole 
• 60683-30-9 ethyl N,N′-diisopropylcarbamimidate 
• 814-49-3 diethyl chlorophosphate 

Downstream Products

• 50716-34-2 3-ethyl-2-methylsulfanyl-benzothiazolium; toluene-4-sulfonate 
• 5231-22-1 3-ethyl-2-ethylsulfanyl-benzothiazolium; toluene-4-sulfonate 
• 1074-18-6 N-ethyl-o-aminothiophenol 
• 2814-60-0 2,2'-azino-bis(3-ethylbenzothiazoline) 

Relevant academic research and scientific papers

A novel synthesis of 2-alkylthiobenzothiazoles and 2-alkylthiobenzoxazoles

3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated by use of O-alkylisoureas as the alkylating reagents. The reactions could be performed under mild reaction conditions in short reaction times, and high yields were obtained using O-primary-alkylisoureas, whereas low yields were obtained with sec-and tert-alkylisoureas.

Alkylation of SH-heterocycles with diethyl phosphite using tetrachloroethylene as an efficient solvent

Treatment of mercapto-heterocyclic compounds with diethyl phosphite in the presence of 4-dimethylaminopyridine (DMAP) in tetrachloroethylene has given the S-ethylated product in good yields and high chemoselectivity. This procedure is compatible with a wide range of SH-compounds such as 1,3,4-oxadiazole-2-thiol, 1,3,4-thiadiazole-2-thiol, benzo[d]thiazole-2-thiol, and substituted benzenethiol. Copyright

An Unusual S- and N-Alkylation of Mercapto Substituted Heterocycles with O,O-Dialkyl Chlorophosphate/Thiophosphate

The reaction of different mercapto substituted heterocycles with O,O-dialkyl chlorophosphate or thiophosphates, gave the corresponding S- and N- alkylated derivatives instead of the expected phosphorylated products.

REACTION OF (2-BENZOTHIAZOLYL)-SULFENAMIDES WITH P-CONTAINING REAGENTS

The title reaction was investigated to find that only substitution reaction on amino group occured when (2-benzothiazoly)sulfenamides 1 reacted with P(NR2)3, whereas the treatment of 1 with (RO)P(NR2)2 gave derivatives of phosphorodiamidothioic acid together with 2-alkylthiobenzothiazole and its isomer in addition to substitution products, and no substitution products obtained when N-substituted analogues of 1 were treated similarly.