2801-21-0

Basic information

• Product Name: 2-Benzothiazolesulfenamide(6CI,7CI,8CI,9CI)
• Synonyms: 2-Benzothiazolesulfenamide(6CI,7CI,8CI,9CI);2-benzothiazylsulfenamide;2-(Aminothio)benzothiazole;2-Benzothiazolesulfenamide
• CAS NO: 2801-21-0
• Molecular Formula: C₇H₆N₂S₂
• Molecular Weight: 182.27
• Product Categories: BENZOTHIAZOLE
• Mol File: 2801-21-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 359°C at 760 mmHg
• Flash Point: 170.9°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 2.46E-05mmHg at 25°C
• Refractive Index: 1.77
• CAS DataBase Reference: 2-Benzothiazolesulfenamide(6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolesulfenamide(6CI,7CI,8CI,9CI)(2801-21-0)
• EPA Substance Registry System: 2-Benzothiazolesulfenamide(6CI,7CI,8CI,9CI)(2801-21-0)

Safety Data

• Hazardous Substances Data: 2801-21-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6N2S2/c8-11-7-9-5-3-1-2-4-6(5)10-7/h1-4H,8H2

Upstream product

• 149-30-4 2-thioxo-3H-1,3-benzothiazole 
• 149-30-4 2-Mercaptobenzothiazole 
• 2492-26-4 sodium 2-mercaptobenzothiazole 

Downstream Products

• 26773-65-9 N-piperidin-2-benzothiazole sulfenamide 
• 102-77-2 4-(benzothiazole-2-sulfenyl)-morpholine 
• 606-57-5 1-nitro-2-naphthylamine 
• 776-34-1 1-amino-4-nitronaphthalene 
• 934-34-9 2-hydroxybenzothiazole 
• 64316-74-1 N-phenyl-N-cyclohexylbenzothiazole-2-sulfenamide 
• 64316-70-7 N-phenyl-N-butylbenzothiazole-2-sulfenamide 
• 120-78-5 di(benzothiazol-2-yl)disulfide 
• 433-17-0 benzothiazole-2-sulfonamide 
• 68835-08-5 tetraethyl-thiophosphorodiamidic acid S-benzothiazol-2-yl ester 
• 2757-92-8 2-(ethylthio)benzothiazole 
• 16407-34-4 3-aethylbenzothiazolin-2-thion 
• 2632-88-4 ethyl N,N'-tetraethyldiamidophosphite 
• 130888-06-1 C₁₉H₃₄N₄O₂P₂S₂ 

Relevant articles and documents

N-Sulfonylcarboxamide as an Oxidizing Directing Group for Ruthenium-Catalyzed C–H Activation/Annulation

N-Sulfonylcarboxamides can act as both a directing group for C–H activation and an internal oxidant in the Ru-catalyzed annulation reaction with alkynes to give isoquinolones. Of all of the N-sulfonylcarboxamides that were studied, the N-(2,6-difluorophenyl)sulfonamide derivatives were found to be the most efficient and led to the formation of an unstable sulfinate byproduct that decomposed into 1,3-difluorobenzene under the reaction conditions. The described isoquinolone synthesis provides an alternative to the currently known traceless annulations of hydroxamic acid and sulfoximine derivatives.

Nitroarylamines via the Vicarious Nucleophilic Substitution of Hydrogen: Amination, Alkylamination, and Arylamination of Nitroarenes with Sulfenamides

A new reaction of sulfenamides with electrophilic arenes under basic conditions is described. The σ adducts formed from nitroarenes and the anions of sulfenamides undergo elimination of thiol to produce the corresponding o- and/or p-nitroanilines. This reaction is analogous to the known alkylation and hydroxylation of nitroarenes via the vicarious nucleophilic substitution of hydrogen (VNS). The reaction gives access to a wide range of substituted nitroanilines, nitronaphthylamines, and aminoheterocycles. By means of the reaction with N-alkyl- and N-arylsulfenamides, it is possible to obtain N-alkylnitroanilines and nitrodiarylamines. By varying the structure of sulfenamide and the reaction conditions, particularly the nature and concentration of the base, it is possible to control the orientation of animation.

Topical carbonic anhydrase inhibitors

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