164072-67-7

Upstream product

• 768-33-2 phenyldimethylsilyl chloride 
• 5390-04-5 pent-1-yn-5-ol 
• 766-77-8 Dimethylphenylsilane 
• 97-99-4 Tetrahydrofurfuryl alcohol 
• 198411-11-9 5-dimethylphenylsilyl-1-(2-tetrahydropyranyloxy)-4-pentyne 
• 3839-31-4 dimethyl(phenyl)silyl lithium 
• 62992-46-5 1-(tetrahydropyranyloxy)-4-pentyn 

Downstream Products

• 1224952-00-4 C₆H₅(CH₃)2SiCHCHCH₂CH₂CH₂OSO₂CH₃ 
• 107398-98-1 (E)-5-(dimethylphenylsilyl)-4-penten-1-ol 
• 259874-71-0 N-((Z)-5-dimethylphenylsilyl-4-pentenyl)-p-toluenesulfonamide 
• 81097-24-7 N-tosyl-(4-pentenyl)amine 
• 259874-72-1 (Z)-5-(Dimethyl-phenyl-silanyl)-pent-4-enylamine 
• 174503-78-7 (Z)-5-dimethylphenylsilyl-1-phenyl-4-penten-1-ol 
• 174503-79-8 (Z)-1-dimethylphenylsilyl-1-undecen-5-ol 
• 174503-80-1 (Z)-7-dimethylphenylsilyl-2-methyl-6-hepten-3-ol 
• 821-09-0 n-Pent-4-enyl alcohol 
• 320399-48-2 (E)-5-(dimethyl(phenyl)silyl)pent-3-en-1-ol 

Relevant academic research and scientific papers

Rh(I)/(III)-N-Heterocyclic Carbene Complexes: Effect of Steric Confinement Upon Immobilization on Regio- and Stereoselectivity in the Hydrosilylation of Alkynes

Rh(I) NHC and Rh(III) Cp* NHC complexes (Cp=pentamethylcyclopentadienyl, NHC=N-heterocyclic carbene=pyrid-2-ylimidazol-2-ylidene (Py?Im), thiophen-2-ylimidazol-2-ylidene) are presented. Selected catalysts were selectively immobilized inside the mesopores

Efficient access to polysubstituted tetrahydrofurans by electrophilic cyclization of vinylsilyl alcohols

Vinylsilyl alcohols undergo intramolecular cyclization to provide di-, tri- or tetrasubstituted-tetrahydrofurans. The influence of the number and position of substituents in the stereoselectivity of the process has been studied. Moreover, DFT calculations

Stereospecific synthesis of cyclobutylboronates through copper(I)-catalyzed reaction of homoallylic sulfonates and a diboron derivative

A copper(I)-catalyzed stereospecific reaction for the preparation of cis- and trans-1-silyl-2-borylcyclobutanes as well as 1-phenyl-2-borylcyclobutanes is reported. (Z)- and (E)-Homoallylic methanesulfonates were converted to the corresponding trans- and

Hydrosilylation of alkynes catalyzed by ruthenium carbene complexes

Hydrosilylation of terminal alkynes with a variety of silanes catalyzed by Cl2(PCy3)2RuCHPh (1) affords mainly the Z-isomer via trans addition in excellent yields. The presence of a hydroxyl group in close proximity to the

Acid-catalyzed cyclization of vinylsilanes bearing a hydroxy group: A new method for stereoselective synthesis of disubstituted tetrahydrofurans

In the presence of a catalytic amount of TsOH or TiCl4, (Z)-5-silyl-4-penten-1-ols ((Z)-1) are smoothly cyclized to 2-silylmethyl-substituted tetrahydrofurans. This cyclization is applicable to the construction of a tetrahydropyran ring. The silyl group and the geometry of the C-C double bond strongly influence the cychzation rate. TBDMS and benzyldimethylsilyl groups considerably accelerate the cyclization in comparison with a dimethylphenylsilyl group, and (E)-vinylsilanes show much lower reactivity than the corresponding (Z)-isomers. The cyclization proceeds by stereospecific syn addition of the hydroxy group. Vinylsilanes 17, 19, and 21, (Z)-5-silyl-4-penten-1-ols bearing a substituent on the methylene tether, smoothly undergo the acid-catalyzed cyclization to give trans-2,5-, cis-2,4-, and trans-2,3-disubstituted tetrahydrofurans, respectively, with moderate to high stereoselectivity. The silyl group of some cychzed products can be easily converted into a hydroxy group with stereochemical retention.

Acid-catalyzed cyclization of vinylsilanes bearing an amino group. Stereoselective synthesis of pyrrolidines

(FORMULA PRESENTED) In the presence of an acid catalyst, vinylsilanes 1 bearing an amino group protected by an electron-withdrawing group were smoothly cyclized to 2-(silylmethyl)pyrrolidines 2. This cyclization was utilized for the stereoselective synthe