164082-79-5

Usage

Chemical classification

1H-Indole, 2-ethyl-4-methoxyis a part of the indole group, which consists of bicyclic heterocyclic organic compounds.

Structure

The compound features a pentagonal carbon ring fused to a pyrrole ring, which contributes to its unique structure.

Substituents

The presence of an ethyl group at position 2 and a methoxy group at position 4 gives 1H-Indole, 2-ethyl-4-methoxy- its specific structure and properties.

Applications

2-Ethyl-4-methoxy-1H-indole is used in various chemical and pharmaceutical applications, such as a building block in the synthesis of organic compounds and as a precursor for the production of pharmaceuticals and agrochemicals.

Importance

The compound's unique structure and functional groups make it an important intermediate in the preparation of a wide range of organic chemicals.

Upstream product

• 164082-78-4 1-[2-(tert-butoxycarbonylamino)-6-methoxyphenyl]-2-butanone 
• 164082-77-3 tert-butyl (3-methoxy-2-methylphenyl)carbamate 
• 19500-02-8 2-methyl-3-methoxyaniline 

Downstream Products

• 164082-86-4 1-[(3-chlorophenyl)methyl]-2-ethyl-4-methoxy-1H-indole 
• 172733-12-9 1-([1,1'-biphenyl]-2-ylmethyl)-2-ethyl-4-methoxy-1H-indole 
• 185298-23-1 1-(2-Benzyl-benzyl)-2-ethyl-4-methoxy-1H-indole 
• 185298-60-6 (3-Aminooxalyl-1-benzenesulfonyl-2-ethyl-1H-indol-4-yloxy)-acetic acid tert-butyl ester 
• 1026450-70-3 (1-Biphenyl-2-ylmethyl-3-chlorooxalyl-2-ethyl-1H-indol-4-yloxy)-acetic acid methyl ester 
• 172733-15-2 [[3-(2-amino-1,2-dioxoethyl)-1-([1,1'-biphenyl]-2-ylmethyl)-2-ethyl-1H-indol-4-yl]oxy]acetic acid methyl ester 
• 185298-19-5 (3-Aminooxalyl-1-benzoyl-2-ethyl-1H-indol-4-yloxy)-acetic acid tert-butyl ester 
• 185298-36-6 [1-(2-Benzyl-benzyl)-2-ethyl-1H-indol-4-yloxy]-acetic acid methyl ester 
• 185501-88-6 [3-Carbamoyl-1-(3-chloro-benzyl)-2-ethyl-1H-indol-4-yloxy]-acetic acid methyl ester 
• 172733-14-1 [[1-([1,1'-biphenyl]-2-ylmethyl)-2-ethyl-1H-indol-4-yl]oxy]acetic acid methyl ester 
• 185298-37-7 (1-Benzoyl-2-ethyl-1H-indol-4-yloxy)-acetic acid tert-butyl ester 
• 185298-27-5 1-(2-Benzyl-benzyl)-2-ethyl-1H-indol-4-ol 
• 185501-87-5 1-(3-Chloro-benzyl)-2-ethyl-4-hydroxy-1H-indole-3-carboxylic acid amide 
• 172733-13-0 1-([1,1'-biphenyl]-2-ylmethyl)-2-ethyl-4-hydroxy-1H-indole 

Relevant academic research and scientific papers

PHARMACEUTICAL COMPOSITIONS CONTAINING THE PHOSPHOLIPASE INHIBITOR SODIUM 3-(2-AMINO-1,2-DIOXOETHYL)-2-ETHYL-1-PHENYLMETHYL)-1H-INDOL-4-YL]OXY]ACETATE

A lyophilized pharmaceutical composition is described which contains Sodium [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Solubilizer, and a Stabilizer. Such compositions are storage stable and readily dissolve in aqueous medium to give injectable solution for treatment of sepsis, etc.

Method for treating sepsis

A novel method of treating and/or preventing sepsis.

Novel sPLA2 inhibitors

A class of novel indole is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

Novel sPLA2 inhibitors

A class of novel indole is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

Method for the treatment of renal dysfunction with spla2 inhibitors

A method is disclosed for the treatment of of the symptoms associated with renal dysfunction by administering to an animal in need thereof a therapeutically effective amount of a sPLA2 inhibitor, such as a 1H-indole-3-glyoxylamide.

METHOD FOR TRATMENT OF NON-RHEUMATOID ARTHRITIS

A method is disclosed for the treatment of non-rheumatoid arthritis by administering to a mammal in need thereof a therapeutically effective amount of an sPLA 2 inhibitor.

Method for the treatment of cystic fibrosis

A method is disclosed for the treatment of cystic fibrosis by administering to a human in need thereof a therapeutically effective amount of an sPLA2inhibitor, such as a 1H-indole-3-glyoxylamide.

Indole sPLA2 inhibitors

A class of novel acylsulfonamide substituted indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2mediated release of fatty acids for treatment of inflammatory diseases.

Combination therapy for the treatment of inflammatory and respiratory diseases

A pharmaceutical composition for the treatment of Inflammatory Disease or Respiratory Disease in mammals, which comprises, as active ingredients, a neutrophil elastase inhibitor and an sPLA2 inhibitor.

SPLA2 inhibitor compounds for treatment of disease

The present invention is directed to compounds for treating inflammatory bowel disease. More specifically, the present invention is directed to 1H-indole-3-glyoxyamide compounds a sPLA2inhibitors for treating inflammatory bowel disease.