164118-56-3Relevant articles and documents
Lewis Acid-Catalyzed Intramolecular [3+2] Cross-Cycloaddition of Aziridine 2,2-Diesters with Conjugated Dienes for Construction of Aza-[n.2.1] Skeletons
Zhan, Yizhou,Liu, Tao,Ren, Jun,Wang, Zhongwen
, p. 17862 - 17866 (2017)
A novel Lewis acid-catalyzed [3+2] intramolecular cross-cycloaddition (IMCC) between aziridine 2,2-diesters and conjugated dienes has been developed. This is the first regiospecific IMCC of intramolecular 1,3-dipolar cycloadditions of azomethine ylides with carbon=carbon double bonds, and supplies a general and efficient strategy for construction of structurally complex and diverse aza-[n.2.1] skeletons. The [3+2]IMCC could be carried out under mild conditions and in gram scale. More importantly, 3-alkyl-substituted aziridines were also successful. The excellent structural diversity, the facile operation and the versatile post-modifications will support the applications of the [3+2]IMCC in natural products synthesis and drugs discovery.
Synthesis of podands with cyanurate or isocyanurate cores and terminal triple bonds
Piron, Flavia,Oprea, Cornelia,Cisma, Crinas,Terec, Anamaria,Roncali, Jean,Grosu, Ion
experimental part, p. 1639 - 1644 (2010/07/04)
The synthesis of podands with cyanuric or isocyanuric acid cores and oligoethyleneoxy pendant arms exhibiting terminal triple bonds or brominated triple bonds is reported. The starting material for cyanuric acid derived podands is commercially available c
