164155-37-7

Usage

General Description

"1-Naphthalenamine, N,N-bis(4-methoxyphenyl)-" is a chemical compound with the molecular formula C28H24N2O2. It is an aromatic amine with two 4-methoxyphenyl groups attached to the nitrogen atom. 1-Naphthalenamine, N,N-bis(4-methoxyphenyl)- is often used as a building block in the synthesis of organic compounds and pharmaceutical drugs. It is also used in the manufacture of dyes, pigments, and other industrial chemicals. 1-Naphthalenamine, N,N-bis(4-methoxyphenyl)- has potential biological activity and is being studied for its potential use in various applications.

Upstream product

• 101-70-2 bis(4-methoxyphenyl)amine 
• 90-13-1 1-Chloronaphthalene 

Relevant academic research and scientific papers

Synthesis of Sterically Congested Triarylamines by Palladium-Catalyzed Amination

An efficient protocol for the palladium-catalyzed synthesis of sterically congested triarylamines from commercially available 1-chloro- or 1-bromonaphthalenes and diarylamines is described. The application of alkyllithium reagents as strong bases and a combination of Pd(OAc)2 and SPhos (2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) plays a crucial role in the success of this otherwise difficult to achieve C-N coupling reaction. A variety of secondary aromatic amines with versatile steric and electronic properties can be successfully used in this transformation to give the desired triarylamines in up to 99 % yield. The obtained products are important structural motifs in hole-transport materials for organic light-emitting diode applications.

Synthesis of sterically congested triarylamines by palladium-catalyzed amination

An efficient protocol for the palladium-catalyzed synthesis of sterically congested triarylamines from commercially available 1-chloro- or 1-bromonaphthalenes and diarylamines is described. The application of alkyllithium reagents as strong bases and a combination of Pd(OAc)2 and SPhos (2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) plays a crucial role in the success of this otherwise difficult to achieve C-N coupling reaction. A variety of secondary aromatic amines with versatile steric and electronic properties can be successfully used in this transformation to give the desired triarylamines in up to 99 % yield. The obtained products are important structural motifs in hole-transport materials for organic light-emitting diode applications. A variety of secondary aromatic amines are coupled with 1-halonaphthalenes to give sterically highly congested triarylamines in up to 99 % yield. The key to the success of this transformation is prior deprotonation of the amine with strong bases such as n-hexyllithium. Copyright