164203-06-9Relevant academic research and scientific papers
Highly enantioselective asymmetric Henry reaction catalyzed by novel chiral phase transfer catalysts derived from cinchona alkaloids
Vijaya, Ponmuthu Kottala,Murugesan, Sepperumal,Siva, Ayyanar
supporting information, p. 10101 - 10109 (2016/11/06)
A new type of di-site chiral phase transfer catalyst has been designed and synthesized from cinchona alkaloids as a chiral precursor. The prepared catalysts are applied in the asymmetric Henry reaction to a wide range of aldehydes using mild concentration
Lipase catalysed resolution of nitro aldol adducts
Sorgedrager, Menno J.,Malpique, Rita,Van Rantwijk, Fred,Sheldon, Roger A.
, p. 1295 - 1299 (2007/10/03)
The kinetic resolution of a range of 1-nitro-2-alkanols by lipase-catalysed esterification using various lipases and succinic anhydride as an acyl donor has been studied. E values of up to 100 were obtained with Novozym 435 in the resolution of 1-nitro-2-pentanol with succinic anhydride in TBME. Acylation with succinic anhydride proved much more enantioselective than with vinyl acetate.
