164203-06-9Relevant articles and documents
Highly enantioselective asymmetric Henry reaction catalyzed by novel chiral phase transfer catalysts derived from cinchona alkaloids
Vijaya, Ponmuthu Kottala,Murugesan, Sepperumal,Siva, Ayyanar
supporting information, p. 10101 - 10109 (2016/11/06)
A new type of di-site chiral phase transfer catalyst has been designed and synthesized from cinchona alkaloids as a chiral precursor. The prepared catalysts are applied in the asymmetric Henry reaction to a wide range of aldehydes using mild concentration
Lipase catalysed resolution of nitro aldol adducts
Sorgedrager, Menno J.,Malpique, Rita,Van Rantwijk, Fred,Sheldon, Roger A.
, p. 1295 - 1299 (2007/10/03)
The kinetic resolution of a range of 1-nitro-2-alkanols by lipase-catalysed esterification using various lipases and succinic anhydride as an acyl donor has been studied. E values of up to 100 were obtained with Novozym 435 in the resolution of 1-nitro-2-pentanol with succinic anhydride in TBME. Acylation with succinic anhydride proved much more enantioselective than with vinyl acetate.