164226-60-2

Upstream product

• 163083-10-1 1-(4-methoxyphenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydroindol-4-one 
• 126-81-8 dimedone 
• 13148-87-3 3-hydroxy-5,5-dimethyl-2-(2-oxopropyl)-2-cyclohex-1-one 
• 176314-15-1 1-(4-methoxyphenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydroindol-4-one oxime 

Downstream Products

• 267402-10-8 1-(4-methoxyphenyl)-2,7,7-trimethyl-4-methylsulfanyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepine 
• 267402-04-0 6H-1-(4-methoxyphenyl)-2,7,7-trimethyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepin-4-thione 

Relevant academic research and scientific papers

Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds

Pyrroloazepinones 8a-j and 9a-j were designed by structural modification of lead compound 3. These compounds were tested on five tumor cell lines to determine the role of the azeto ring and the 2-methyl substituent in the cytotoxicity of compound 3. Our r

Synthesis of the new triheterocyclic system C3N-C4N-C6N, 3-aryl- 2,5,5-trimethyl-9a-methylsulfanyl-9-phenoxy-4,5,6,8,9,9a-hexahydro-3H- azeto[1,2-a]pyrrolo[3,2-c]azepin-8-ones

The regio- and stereoselective synthesis of the cis-3-aryl-2,5,5- trimethyl-9a-methylsulfanyl-9-phenoxy-4,5,6,8,9,9a-hexahydro-3H-azeto[1,2- a]pyrrolo[3,2-c]azepin-8-ones (1) was performed. A four-step sequence, which yields are good, constitutes the firs

Synthesis and spectral properties of 6H-1-(2-, 3- and 4-R-phenyl)-2,7,7-trimethyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepine-4- ones

The preparation of novel 4,5,7,8-tetrahydropyrrolo[3,2-c]azepin-4-ones is described. The structure of all the products was corroborated by ir, mass spectrometry and 1H and 13C-nmr.