164299-71-2

Basic information

• Product Name: N-Benzotriazol-1-ylmethyl-nicotinamide
• Synonyms: N-Benzotriazol-1-ylmethyl-nicotinamide
• CAS NO: 164299-71-2
• Molecular Formula: C₁₃H₁₁N₅O
• Molecular Weight: 253
• Mol File: 164299-71-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Benzotriazol-1-ylmethyl-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzotriazol-1-ylmethyl-nicotinamide(164299-71-2)
• EPA Substance Registry System: N-Benzotriazol-1-ylmethyl-nicotinamide(164299-71-2)

Safety Data

• Hazardous Substances Data: 164299-71-2(Hazardous Substances Data)

Upstream product

• 28539-02-8 1-Hydroxymethyl-1H-benzotriazole 
• 98-92-0 nicotinamide 
• 95-14-7 1,2,3-Benzotriazole 
• 50-00-0 formaldehyd 

Relevant articles and documents

Generalization of the Benzotriazole-Mediated Introduction of N-Substituents into Amides

N-(Benzotriazol-1-ylmethyl) amides 2, easily available by condensation of BtCH2OH with amides, are used for the preparation of a variety of N-substituted amides such as the homoallyl, 1,3-butadienyl, and 2,2-diphenylcyclopropyl derivatives by displacement

New N-mannich bases

Amides, aldehydes and benzotriazole or morpholine react, with the elimination of water to form N-Mannich bases or N,N′-arylidene symmetrical diamides in good or very good yields. We also found that amides, aldehydes and 1,2,4-triazole react to form a new N-[1-(1H-1,2,4-triazol-1-yl)alkyl]amides with a 58-85% yield.