1643-39-6

Basic information

• Product Name: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL
• Synonyms: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL;4,6-Di-tert-butyl-2-aminophenol;2-AMino-4,6-di-tert.-butyl-phenoxyl
• CAS NO: 1643-39-6
• Molecular Formula: C₁₄H₂₃NO
• Molecular Weight: 221.34
• Mol File: 1643-39-6.mol
• Article Data: 29

Chemical Properties

• Melting Point: 171-172 °C
• Boiling Point: 297.9±40.0 °C(Predicted)
• Appearance: /
• Density: 0.990±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 11.36±0.23(Predicted)
• CAS DataBase Reference: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(1643-39-6)
• EPA Substance Registry System: 2-AMINO-4,6-DI-TERT-BUTYLPHENOL(1643-39-6)

Safety Data

• Hazardous Substances Data: 1643-39-6(Hazardous Substances Data)

Usage

General Description

2-AMINO-4,6-DI-TERT-BUTYLPHENOL is a chemical compound with the molecular formula C14H23NO. It is commonly used as an antioxidant in various industrial applications, including in the production of polymers and plastics. The compound is a white crystalline solid at room temperature and is insoluble in water. It is known for its ability to inhibit the oxidation of other substances, making it a valuable additive in products where stability and shelf life are important considerations. Additionally, it has been used as a stabilizer in fuels and lubricants to prevent degradation from exposure to oxygen and other reactive substances.

Upstream product

• 96-76-4 2,4-di-tert-Butylphenol 
• 20039-94-5 2,4-di-tert-butyl-6-nitrophenol 
• 52184-14-2 2,4-bis(1,1-dimethylethyl)-6-[(2-nitrophenyl)diazenyl]phenol 
• 52184-29-9 2-nitro-4-chloro-2'-hydroxy-3',5'-di-tert-butylazobenzene 
• 1188-01-8 dl-alanylglycine 
• 3383-21-9 3,5-di-tert-butyl-o-benzoquinone 
• 615-82-7 DL-Leucyl-glycin 
• 1020-31-1 3,5-Di-tert-butylcatechol 
• 873055-54-0 carbonic acid 2,4-di-tert-butyl-phenyl ester methyl ester 
• 201023-39-4 cyclo-L-phenylalanyl-L-phenylalanine 
• 325463-16-9 3,5-di-tert-butyl-1,2-benzoquinone 1-oxime 
• 52749-93-6 4-azido-2,4,6-tri-t-butyl-2,5-cyclohexadien-1-one 

Downstream Products

• 118041-64-8 2,4-Di-tert-butyl-6-cyclohexylideneamino-phenol 
• 132039-87-3 2,4-di-tert-butyl-6-<(o-hydroxy-α-methylbenzylidene)amino>phenol 
• 103661-06-9 2,4-di-tert-butyl-6-{[(2-hydroxyphenyl)methylene]amino}phenol 
• 132056-61-2 2,4-di-tert-butyl-6-<(5-chloro-2-hydroxy-α-methylbenzylidene)amino>phenol 
• 124980-83-2 4-(2-Hydroxy-3,5-di-tert-butylphenylimino)-2,6-di-tert-butyl-2,5-cyclohexadien-1-one 
• 86759-35-5 4,6-di-tert-butyl-N-(2-hydroxy-3,5-di-tert-butyl-phenyl)-o-iminobenzoquinone 
• 77358-25-9 5,7-Di-tert-butyl-2,3-dihydro-2-(<13C>methyl)-2,2-diphenyl-1,3,2λ⁵-benzoxazaphosphol 
• 86314-36-5 5,7-Di-tert-butyl-2-phenylspiro<1,3,2λ⁵-benzoxaphosphol-2(3H),5'-λ⁵-dibenzophosphol> 
• 60043-08-5 N-(3,5-di-tert-butyl-2-hydroxyphenyl)acetamide 
• 60042-99-1 C₂₈H₄₂N₂O₂ 

Relevant articles and documents

Molecular structures, DFT studies and their photophysical properties in solution and solid state. Microwave-assisted multicomponent synthesis of organotin bearing Schiff bases

A couple of luminescent organotin compounds derivated from ligands-ONO were obtained by multicomponent microwave assisted synthesis in short time (15 min) and good yields: ((E)-8, 8-8-diphenylbenzo[d] naphtho [1,2-h][1,3,6,2] dioxazastannonine (1) and (E)

Fluorescent Molecular Rotors of Organoboron Compounds from Schiff Bases: Synthesis, Viscosity, Reversible Thermochromism, Cytotoxicity, and Bioimaging Cells

We report the design, synthesis, and characterization of two new fluorescent molecular rotors of boron derived from Schiff bases: (2,4,8,10-tetra-tert-butyl-6-phenyldibenzo[d,h][1,3,6,2]dioxazaboronine (3) and 1,4-bis(2,4,8,10-tetra-tert-butyldibenzo[d,h][1,3,6,2]dioxazaboronin-6-yl)benzene (4), as well as the free ligand 2-[[(3,5-di-tert-butyl-2-hydroxyphenyl)imino]methyl]-4,6-di-tert-butylphenol 1. All compounds were fully characterized by NMR (1H,11B, and13C), IR, UV/vis, fluorescence spectroscopy, and high-resolution mass spectrometry. The crystal structures of 3 and 4 showed tetracoordinated boron atoms with semiplanar skeleton ligands. The free rotation of the fluorescent molecular rotor, only observed in the binuclear compound, was decreased with increasing viscosity, while the quantum yield was increased. Interestingly, the property of reversible thermochromism was found in organoboron 4 in the solid state. DFT calculations to determine the both complexes have free rotation around the CPh-B1 bond. The boron compounds 3 and 4 have shown low cytotoxicity activity in cell line A-431 and low green staining in cells.

Metal-Free Oxidative Condensation of Catechols, Aldehydes and NH4OAc towards Benzoxazoles

Benzoxazoles extensively exist in biologically active compounds, natural products, pharmaceuticals and functional materials. Thus, facile and green synthesis of such valuable compounds from easily available substrates will make a contribution to drug, material, and fine chemistry. A method for the synthesis of benzoxazoles from catechols, aldehydes and ammonium acetate is developed using NaIO4 as oxidant under metal- and additive-free conditions. A broad range of benzoxazoles including some fluorescent whitening agents, JTP-426467 and tafamidis analogues are synthesized in 56–95% yields with outstanding functional group tolerance. Mechanistic investigations suggest that an interesting o-iminocyclohexa-diene alcohol intermediate is involved in the reaction. These salient features of the protocol make it an alternative for the synthesis of benzoxazoles. (Figure presented.).

A new bis-phenolate mesoionic carbene ligand for early transition metal chemistry

We report the synthesis of a new pincer-type triazolylidene ligand precursor H3L[Cl] with redox-active 3,5-di-tert-butylphenolate substituents on a multigram scale following a converging ten-step route. The potential of this new mesoionic carbe