1643501-27-2Relevant academic research and scientific papers
A concise approach to polysubstituted oxazoles from N-acyl-2-bromo enamides via a copper(i)/amino acid-catalyzed intramolecular C-O bond formation
Liu, Bingjie,Zhang, Yueteng,Huang, Gang,Zhang, Xinting,Niu, Pengfei,Wu, Jie,Yu, Wenquan,Chang, Junbiao
, p. 3912 - 3923 (2014/06/09)
A straightforward and efficient copper(i)/amino acid-catalyzed intramolecular Ullmann-type C-O coupling reaction has been developed. This protocol affords a facile methodology for the synthesis of a series of novel 2,4,5-substituted oxazoles from readily accessible N-acyl-2-bromo enamides under mild conditions. This journal is the Partner Organisations 2014.
