1643653-99-9Relevant academic research and scientific papers
Versatile CuI/Pd0 dual catalysis for the synthesis of quaternary α-allylated carbonyl compounds: Development, mechanistic investigations and scope
Nahra, Fady,Mace, Yohan,Boreux, Arnaud,Billard, Francois,Riant, Olivier
, p. 10970 - 10981 (2014)
We report herein a versatile cooperative dual catalysis reaction based on a CuI/Pd0 system. Mechanistic investigation shows that every component plays a crucial role in determining the reaction outcome. The reaction is successfully extended to various substrates; such as α,β-unsaturated ketones, malonates and coumarins. The strategy tolerates different substitution patterns and affords good yields for each family of substrates.
