1643770-99-3

Basic information

• Product Name: (R)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-fluoro-3-(4-methoxyphenyl)propanoate
• CAS NO: 1643770-99-3
• Molecular Weight: 428.46
• Mol File: 1643770-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-fluoro-3-(4-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-fluoro-3-(4-methoxyphenyl)propanoate(1643770-99-3)
• EPA Substance Registry System: (R)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-fluoro-3-(4-methoxyphenyl)propanoate(1643770-99-3)

Safety Data

• Hazardous Substances Data: 1643770-99-3(Hazardous Substances Data)

Upstream product

• 103-80-0 phenylacetyl chloride 
• 1214712-10-3 (R)-2-fluoro-3-(4-methoxyphenyl)propanoic acid 
• 1643771-07-6 3-hydroxy-2,2-dimethyl-1-(2-phenylacetyl)imidazolidin-4-one 
• 1643771-06-5 3-(benzyloxy)-2,2-dimethyl-1-(2-phenylacetyl)imidazolidin-4-one 

Downstream Products

• 481038-59-9 (3R)-3-benzylmorpholine 
• 1643770-71-1 C₂₁H₂₄FNO₃ 
• 1643770-65-3 C₂₁H₂₄FNO₃ 
• 1643770-88-0 C₂₁H₂₄FNO₃ 
• 77897-23-5 (3S)-3-benzylmorpholine 

Relevant articles and documents

Stereoelectronic basis for the kinetic resolution of n-heterocycles with chiral acylating reagents

The kinetic resolution of N-heterocycles with chiral acylating agents reveals a previously unrecognized stereoelectronic effect in amine acylation. Combined with a new achiral hydroxamate, this effect makes possible the resolution of various N-heterocycles by using easily prepared reagents. A transition-state model to rationalize the stereochemical outcome of this kinetic resolution is also proposed.