1643961-99-2

Upstream product

• 1643961-88-9 N-(4-bromo-2,6-diisopropylphenyl)-N'-(2,6-diisopropylphenyl)ethane-1,2-diamine 
• 80058-84-0 4-bromo-2,6-diisopropylaniline 
• 1647066-04-3 C₂₇H₃₈BrN₂⁽¹⁺⁾ 
• 169772-26-3 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid 
• 1643961-87-8 N¹-(4-bromo-2,6-diisopropylphenyl)-N²-(2,6-diisopropylphenyl)-oxalamide 
• 1643961-90-3 1-(4-bromo-2,6-diisopropylphenyl)-3-(2,6-diisopropylphenyl)imidazolidine 

Relevant academic research and scientific papers

Synthesis of substituted imidazolidines: Base-stable precursors of 4,5-dihydro-1h-imidazol-3-ium salts and N-heterocyclic carbenes

The present work establishes a new synthetic route that leads to substituted azolium salts. The base stable 1-(4-bromo-2,6-diisopropylphenyl)-3- (2,6-diisopropylphenyl)imidazolidine and 1,3-bis(4-bromo-2,6-diisopropylphenyl) imidazolidine were synthesized and the 4-Br substituents converted into various functional groups through Br/Li exchange or Pd-catalyzed cross-coupling reactions (Suzuki, Sonogashira, and vinylation). The substituted imidazolidines were oxidized, by using chloranil or N-bromosuccinimide, to provide the respective azolium salts, which are convenient precursors to N-heterocyclic carbenes. Copyright