16441-25-1

Basic information

• Product Name: (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE
• Synonyms: 2-(2-Phenylthiazol-4-yl)acetonitrile
• CAS NO: 16441-25-1
• Molecular Formula: C₁₁H₈N₂S
• Molecular Weight: 200.26
• Mol File: 16441-25-1.mol

Chemical Properties

• Boiling Point: 386.9°Cat760mmHg
• Flash Point: 187.8°C
• Appearance: /
• Density: 1.223g/cm³
• Vapor Pressure: 3.42E-06mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE(16441-25-1)
• EPA Substance Registry System: (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE(16441-25-1)

Safety Data

• Hazardous Substances Data: 16441-25-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE is utilized as a building block for the production of agrochemicals. Its incorporation into these products can enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Organic Synthesis Research and Development:
(2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE is employed as a research compound in the development of new organic synthesis methods. Its potential biological activity makes it a valuable candidate for exploring novel chemical reactions and applications in the field of organic chemistry.
Used in Industrial Applications:
Beyond its use in pharmaceuticals and agrochemicals, (2-PHENYL-1,3-THIAZOL-4-YL)ACETONITRILE may also have other industrial applications. Its versatility as a chemical compound allows it to be explored for various uses in different industries, expanding its potential impact and utility.

InChI:InChI=1/C11H8N2S/c12-7-6-10-8-14-11(13-10)9-4-2-1-3-5-9/h1-5,8H,6H2

Upstream product

• 4771-31-7 2-phenyl-4-chloromethylthiazole 
• 72011-24-6 1,4,7,10,13,20-Hexaoxa<13.1>(1,2)benzenophan 
• 773837-37-9 sodium cyanide 
• 2227-79-4 benzenecarbothioamide 
• 143-33-9 sodium cyanide 

Downstream Products

• 67411-77-2 1-(2,6-dihydroxy-4-methyl-phenyl)-2-(2-phenyl-thiazol-4-yl)-ethanone 
• 51625-78-6 1-(2,4-dihydroxy-phenyl)-2-(2-phenyl-thiazol-4-yl)-ethanone 
• 55315-38-3 5-(2-phenyl-thiazol-4-ylmethyl)-1⁽²⁾H-tetrazole 

Relevant articles and documents

Synthesis and Insecticidal Activity of Novel Thiazole Acrylonitrile Derivatives

A series of novel thiazole acrylonitrile derivatives was designed and synthesized utilizing NC-510 as a precursor. Their structures were characterized by NMR spectrometry, MS, and elemental analysis. The results of bioassay indicated that some of these ti

Acrylonitrile type compound and use thereof

The invention discloses an acrylonitrile type compound as shown in a formula (I) as well as a preparation method and application of the acrylonitrile type compound, (as shown in the description), wherein Ar1, Ar2, R, R1, R2, X, Y and n have definitions as

Thiazolyl acrylonitrile compound and use thereof

The invention discloses a thiazolyl acrylonitrile compound with novel structure or stereoisomers thereof. The compound has a general formula as shown in a general formula I. R is selected from C1-C6 alkyl, halogenated C1-C6 alkyl, C3-C8 cycloalkyl and C1-

Phenyl thiazolyl acrylonitrile compound and use thereof

The invention discloses a phenyl thiazolyl acrylonitrile compound with novel structure or stereoisomers thereof. The compound has a structure as shown in a formula I. R1 is selected from C1-C6 alkyl, halogenated C1-C6 alkyl, C3-C8 cycloalkyl, C1-C6 alkylo

2- [...] azoly acrylonitrile compound and use thereof

The invention discloses a 2-chloro thiazolyl acrylonitrile compound or a stereisomer thereof with a novel structure. The structure of the compound is shown as the general formula I in the specification, wherein R is one of alkyl of C1-C6, halogenated alkyl of C1-C6, cycloalkyl of C3-C8 and alkoxy of C1-C6; Q is selected from the group shown as the specification; R1 is one of H, halogen, methyl and trifluoromethyl; R2 is one of H and halogen. The compound in the general formula I has excellent insect and mite killing activity, and can be used for preventing and controlling insects and mites.

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT) and Chagas disease. Drugs currently available to treat these neglected diseases leave much to be

Pyrazolyl thiazolyl acrylonitrile compounds and use thereof

The present invention discloses a novel structure pyrazolyl thiazolyl acrylonitrile compound or a stereoisomer thereof, wherein the structure of the compound is represented by a general formula I, R1 is selected from C1-C6 alkyl, halogenated C1-C6 alkyl,

Acrylonitrile compound, and preparation method and application thereof

The invention discloses an acrylonitrile compound shown as the formula (I), and a preparation method and application thereof. Ar , Ar, R, W and Y in the formula (I) have definitions given in the description. The compound in the formula (I) has insec

HETEROCYCLIC COMPOUNDS AND USE OF SAME

Novel heterocyclic compounds are provided which display useful efficacy in the treatment of diseases caused by trypanosomatids. Particularly, the compounds of the invention are useful in the treatment of HAT and/or Chagas disease and/or Animal African trypanosomiasis (AAT).

Etylene derivatives and pesticides containing said derivatives

Ethylene derivatives of formula (I): where Q is an unsubstituted or substituted phenyl or heterocyclic group, especially a 4-thiazolyl, 1- or 3-pyrazolyl, 1,3-oxazol-4-yl, phenyl or pyridyl group; E is a substituent such as a cyano group; A is a substituent such as a 4-pyrazolyl or thiazolyl group; and B is a substituent such as an alkylcarbonyl group. Agricultural chemicals and agents for preventing the attachment of aquatic organisms containing one or more such ethylene derivatives.