1644186-25-3Relevant academic research and scientific papers
Rhodium-catalyzed stereoselective amination of thioethers with n-mesyloxycarbamates: DMAP and Bis(DMAP)CH2Cl2 as key additives
Lebel, Hélène,Piras, Henri,Bartholoméüs, Johan
supporting information, p. 7300 - 7304 (2014/07/21)
A stereoselective Rh-catalyzed intermolecular amination of thioethers using a readily available chiral N-mesyloxycarbamate to produce sulfilimines in excellent yields and diastereomeric ratio is described. A catalytic mixture of 4-dimethylaminopyridine (DMAP) and bis(DMAP)CH2Cl2 proved pivotal in achieving high selectivity. The X-ray crystal structure of the (DMAP)2·[Rh2{(S)-nttl}4] complex was obtained and mechanistic studies suggested a RhII-RhIII complex as the catalytically active species.
