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1-Chloro-2-(trifluoromethoxy)ethane, with the chemical formula C3H2ClF3O, is an organochlorine compound characterized by the presence of a chlorine atom and a trifluoromethoxy group attached to an ethyl backbone. This unique molecular structure endows it with specific chemical properties that make it suitable for various applications in the chemical and pharmaceutical industries.

1645-95-0

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1645-95-0 Usage

Uses

Used in Pharmaceutical Industry:
1-Chloro-2-(trifluoromethoxy)ethane is used as a reactant for the synthesis of heteroarylacryloylaminoalkyl benzenesulfonamides, which are compounds with potential cardiovascular applications. The incorporation of 1-chloro-2-(trifluoromethoxy)ethane into the synthesis process allows for the creation of new drug candidates that can target and treat various cardiovascular conditions, thereby contributing to the development of innovative therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 1645-95-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,4 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1645-95:
(6*1)+(5*6)+(4*4)+(3*5)+(2*9)+(1*5)=90
90 % 10 = 0
So 1645-95-0 is a valid CAS Registry Number.

1645-95-0Downstream Products

1645-95-0Relevant academic research and scientific papers

CYCLISIERUNGEN UNTER BETEILIGUNG VON FLUORIDIONEN, 3. MITTEIL. TEILFLUORIERTE 1.3- UND 1.4-DIOXANE

Siegemund, Guenter,Schwertfeger, Werner

, p. 133 - 144 (2007/10/02)

Cyclization of 2-(2-chloroethoxy)-perfluorcarboxylic acid halides 3 with alkali metal fluoride gives 2.3-perfluoro-1.4-dioxanes 6 with yields up to 84 percent.This reaction is also used for the preparation of 4.5.6-perfluoro-1.3-dioxanes 12 starting from 3-chloromethoxyperfluorocarbonyl compounds 11. - The preparation of starting materials is described.

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