164584-67-2Relevant academic research and scientific papers
Synthesis of 4-amino substituted 1,8-naphthalimide derivatives using palladium-mediated amination
Fleming, Cassandra L.,Ashton, Trent D.,Pfeffer, Frederick M.
, p. 135 - 143 (2014/06/23)
Successful amination of 4-bromo-1,8-naphthalimides with 'lengthy' imide N-functionality has been achieved using a general palladium mediated approach (conventional thermal protocols were sub-optimal). Only readily available Pd/ligand combinations were considered and the resulting Buchwald-Hartwig procedure using Pd2(dba)3, Xantphos and Cs 2CO3 is high yielding, relatively mild (40-80 °C, 24 h, yields 50-90%), requires only a modest excess of amine (3.0 equiv) and works equally well with other imide N-substituents. As such, the protocol complements existing methods but is superior for more complex substrates. Herein we compare this Pd mediated approach to the methods most commonly used and further demonstrate its utility by synthesising a number of new, highly fluorescent, 4-aminonaphthalimides.
Switching off FRET by analyte-induced decomposition of squaraine energy acceptor: A concept to transform 'turn off' chemodosimeter into ratiometric sensors
Yu, Haibo,Fu, Meiyan,Xiao, Yi
scheme or table, p. 7386 - 7391 (2011/09/12)
FRET cassette-type sensors, SN-1 and SN-2, which contain two naphthalimide donors and a squaraine acceptor, have been developed on the concept of switching off FRET through removing the spectral overlap by the analyte-induced decompositions of acceptor ch
