1646-75-9

Basic information

• Product Name: ALDICARB-OXIME
• Synonyms: 2-methyl-2-(methylthio)propionaldehydeoxime;ALDICARB-OXIME;Propanal, 2-methyl-2-(methylthio)-, oxime;Propionaldehyde, 2-methyl-2-(methylthio)-, oxime.;2-methyl-2-(methylthio)-propanal oxime;Aldicarb-oxime, 10 μg /μL in acetonitrile;2-methyl-2-(methylsulfanyl)propanaldoxime
• CAS NO: 1646-75-9
• Molecular Formula: C₅H₁₁NOS
• Molecular Weight: 133.21
• EINECS: 216-709-5
• Mol File: 1646-75-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 21.1°C
• Boiling Point: 210°C
• Flash Point: 81.1°C
• Appearance: /liquid
• Density: 1.037 (estimate)
• Vapor Pressure: 0.076mmHg at 25°C
• Refractive Index: 1.5216 (estimate)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: ALDICARB-OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: ALDICARB-OXIME(1646-75-9)
• EPA Substance Registry System: ALDICARB-OXIME(1646-75-9)

Safety Data

• Hazardous Substances Data: 1646-75-9(Hazardous Substances Data)

Usage

Uses

Temik Oxime is an intermediate in the synthesis of Aldicarb-d3 Sulfoxide (A514667), which is a labeled Aldicarb Sulfoxide (A514665). Aldicarb Sulfoxide is an analog of Aldicarb (A514650) detected in agricultural products as pesticide residue.

Definition

ChEBI: The oxime resulting from the formal condensation of 2-methyl-2-(methylsulfanyl)propanal with hydroxylamine. Addition of the oxime group to methyl isocyanate forms the final step in the synthesis of the systemic insecticide aldicarb.

General Description

Clear colorless,viscous liquid with an unpleasant sulfurous or musty odor.

Air & Water Reactions

Sensitive to heat. Water soluble. May decompose with prolonged exposure to moisture.

Reactivity Profile

ALDICARB-OXIME is incompatible with oxidizers, acids and alkalis [(NTP, 1992]. Several explosions or violent decompositions have occurred during distillation of alkoxides, which may be attributable to the formation of peroxides of various types. This is especially the case in the presence of acid, Chem. Eng. News, 1974, 52(35), 3. A nickel catalyzed aldoxime rearrangement to an amide, went out of control after changing the solvent employed, J. Loss Prev., 1993, 6(2), 69.

Fire Hazard

ALDICARB-OXIME is combustible.

InChI:InChI=1/C5H11NOS/c1-5(2,8-3)4-6-7/h4,7H,1-3H3/b6-4+

Upstream product

• 116-06-3 temik 

Downstream Products

• 116-06-3 temik 
• 14357-44-9 2-methanesulfonyl-2-methyl-propionaldehyde oxime 
• 7635-32-7 2-methanesulfinyl-2-methyl-propionaldehyde oxime 

Relevant articles and documents

A fluorescence detection scheme for capillary electrophoresis of N- methylcarbamates with on-column thermal decomposition and derivatization

This paper describes a fluorescence detection method for N- methylcarbamate (NMC) pesticides in micellar electrokinetic chromatography (MEKC) separation. Fulfillment of the fluorescence detection hinged on the discovery that quaternary ammonium surfactants (particularly cetyltrimethylammonium bromide, CTAB), besides serving as hydrophobic pseudophases in MEKC, are also capable of catalyzing the thermal decomposition of NMCs to liberate methylamine. Thus, a multifunctional MEKC medium consisting of borate buffer, CTAB, and derivatizing components (o- phthaldialdehyde/2-mercaptoethanol) was formulated, which allowed first normal MEKC separation, subsequent thermal decomposition, and finally in situ derivatization of NMCs. With careful optimization of the operation conditions, fluorescence detection of 10 NMC compounds was achieved, with column efficiencies typically higher than 50 000 and detection limits better than 0.5 ppm. The present work represents an unprecedented effort in capillary electrophoresis (CE), in which an intact capillary was consecutively utilized as chambers for separation, decomposition, derivatization, and detection, without involving any interfacing features. The success in the implementation of such a detection system resulted in strikingly simple instrumentation as compared with the traditional postcolumn fluorescence determination of NMCs by reversed-phase HPLC. Similar protocols should be workable in the determination of a wide range of pesticides and pharmaceuticals in CE formats.