164648-32-2

Basic information

• Product Name: Benzonitrile, 4-[(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-
• CAS NO: 164648-32-2
• Molecular Formula: C13H13N3O2
• Molecular Weight: 243.265
• Mol File: 164648-32-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-(164648-32-2)
• EPA Substance Registry System: Benzonitrile, 4-[(4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-(164648-32-2)

Safety Data

• Hazardous Substances Data: 164648-32-2(Hazardous Substances Data)

Upstream product

• 77-48-5 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione 
• 104-85-8 para-methylbenzonitrile 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 
• 17201-43-3 4-cyanobenzyl bromide 

Downstream Products

• 164648-33-3 4-[(4,5-Dihydro-5,5-dimethyl-2,4(3H)-dioxo-1H-imidazol-3-yl)methyl]-benzenemethylamine-hydrochloride 

Relevant articles and documents

Preparation method of N-(aryl/heteroaryl) alkyl-diamide

The invention relates to a preparation method of N-(aryl/heteroaryl)alkyl- diamide, which comprises the following steps: under the protection of nitrogen, sequentially adding transition metal, phosphine or nitrogen ligand, cocatalyst, alkali, solvent, Nhalogenated cyclodiamide, alkyl aromatic ring or alkyl heteroaromatic ring compound into a reaction container, carrying out oxidative amination reaction at 80-140 DEG C, and till the reaction concludes after 6-48 hours, evaporating and drying a solvent and carrying out column chromatography separation to obtain an N (aryl/heteroaryl) alkyl diamide compound. The invention is simple in synthesis process, mild in reaction condition, high in yield and easy to industrialize.

AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND THEIR USE IN THE TREATMENT OF OBESITY

Amino acid derivatives, suitable for the treatment of obesity. The following compound is exemplary of the class: (R)-N2-(diphenylacetyl)-N-[(4-hydroxyphenyl) methyl]-argininamide-acetate.