164735-80-2

Upstream product

• 865302-09-6 (2E,5S,6R,7S) 8-benzyloxy-6-(t-butyldimethylsilyloxy)-1-chloro-1,1-dideuterio-5,7-dimethyloct-2-ene 
• 155299-98-2 (3S,4R,5S)-6-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexanal 
• 164735-79-9 (2E,5S,6R,7S) 8-benzyloxy-6-(t-butyldimethylsilyloxy)-1,1-dideuterio-5,7-dimethyloct-2-en-1-ol 
• 155299-99-3 (E)-(5S,6R,7S)-8-Benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-5,7-dimethyl-oct-2-enoic acid ethyl ester 

Relevant academic research and scientific papers

Biosynthesis of Tetronasin: Part 4, Preparation of Deuterium Labelled C19-C26, C17-C26, C11-C26 and C3-C26 Polyketide Fragments as Putative Biosynthetic Precursors of the Ionophore Antibiotic Tetronasin (ICI 139603)

Six deuterium labelled N-acylcysteamine polyketide derivatives (3) - (8) have been prepared as putative precursors for incorporation in studies of the biosynthesis of the ionophore antibiotic tetronasin (1).The route to these compounds was designed to be

Biosynthesis of Tetronasin: Part 3. Preparation of Deuterium Labelled Tri- and Tetraketides as Putative Biosynthetic Precursors of Tetronasin

The preparation of seven deuterium labelled N-acetyl cysteamine thioesters (2a), (2b), (3a), (3b), (4), (5) and (6) as putative biosynthetic precursors of the acyl tetronic acid ionophore tetronasin is described.