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2-Hydroxy-3-o-tolyloxy-propylfluorid, also known as 2-hydroxy-3-(2-methylphenoxy)propyl fluoride, is a chemical compound with the molecular formula C10H13FO2. It is a colorless liquid at room temperature and is soluble in water. 2-Hydroxy-3-o-tolyloxy-propylfluorid is primarily used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It is known for its ability to act as a protecting group for hydroxyl groups in organic molecules, which is crucial in the synthesis of complex organic compounds. The compound's structure features a hydroxyl group, a fluoromethyl group, and an o-tolyloxy (2-methylphenoxy) group, which together contribute to its reactivity and utility in chemical reactions.

1649-95-2

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1649-95-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1649-95-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,4 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1649-95:
(6*1)+(5*6)+(4*4)+(3*9)+(2*9)+(1*5)=102
102 % 10 = 2
So 1649-95-2 is a valid CAS Registry Number.

1649-95-2Relevant academic research and scientific papers

Regioselectivity of the ring opening of propene oxides bearing electron-withdrawing substituents at the methyl group with Olah's reagent

Skupin, Rolf,Haufe, Guenter

, p. 157 - 165 (2007/10/03)

The regiochemistry of the hydrofluorination of terminal epoxides with Olah's reagent (Py·9HF) is dependent on the electron-withdrawing character of the β-substituents. Phenoxy ethers with different substitution patterns of the aromatic ring and several N-heterocycles were examined as β-substituents.

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