164907-50-0Relevant academic research and scientific papers
Attempt to rationalize the diastereoselectivity in the addition of ester enolate to optically active α,β-epoxyaldehydes
Nacro,Baltas,Gorrichon
, p. 14013 - 14030 (2007/10/03)
Aldol condensations on α,β-epoxyaldehyde having a remote alkoxy group have been realized. A rationalization of the outcome of this condensation is discussed, relying on the dominant conformers revealed by molecular modeling of anti and syn γ,δ-epoxy β-hyd
Total Synhesis of Balanol, Part 1. Enantioselective Synthesis of the Hexahydroazepine Ring via Chiral Epoxides and Azidirines
Tanner, David,Almario, Antonio,Hoegberg, Thomas
, p. 6061 - 6070 (2007/10/02)
Three differents routes to the hexahydroazepine unit of the natural products balanol (1) and ophicordin (2) are described.The common starting material is the chiral epoxy alcohol 3 which is converted to the balanol degradation product 10 (Scheme 1) or to
