164930-80-7Relevant academic research and scientific papers
Six-membered cyclic semiaminal as intermediate in the synthesis of thiazoles from thiosemicarbazide and α-haloketones
Mamedov, V. A.,Berdnikov, E. A.,Valeeva, V. N.,Ismaev, I. E.,Rizvanov, I. Ch.,et al.
, p. 1879 - 1882 (1993)
Cyclization of thiosemicarbazide with methyl 3-chloro-2-oxo-3-phenylpropionate in MeCN results in 5-hydroxy-2-imino-5-methoxycarbonyl-6-phenylperhydro-1,3,4-thiadiazine.The structure of the product has been confirmed using spectral (IR, 1H, 13C, 13C N
Synthesis of Some New Annellated 1,2,4-Triazole Systems from Methyl 5-Phenyl-2-hydrazinothiazolecarboxylate
Mamedov, V. A.,Valeeva, V. N.,Antokhina, L. A.
, p. 355 - 358 (2007/10/03)
The heterocyclization of hydrazides, prepared from methyl 5-phenyl-2-hydrazinothiazole-4-carboxylate and organic acids or their anhydrides, leads to the production of thiazolotriazoles which do not undergo rearrangement to the corresponding thiazolotriazoles under the action of mineral acids.The 2-trifluoroacetylhydrazine derivative does not cyclize, even under severe conitions.
