164931-85-5Relevant articles and documents
Asymmetric Synthesis of cis -(S, R)-3-Amino-4-fluoro-1-methylpyrrolidine
Bian, Jianwei,Cheung, Chiming,Fei, Zhongbo,Gao, Hongjun,Liu, Weipeng,Shen, Qirong,Xiong, Xin,Zhang, Jinzhu
, p. 1228 - 1230 (2019)
The development of the stereoselective synthesis of cis -(S, R)-3-amino-4-fluoro-1-methylpyrrolidine is described starting from chiral, non-racemic 1-[(3 S,4 S)-3-azido-4-hydroxypyrrolidin-1-yl]-2,2,2-trifluoroethan-1-one. Two sets of deoxyfluorination co