16501-75-0Relevant articles and documents
N-Substituted cyanacetohydrazides in the synthesis of 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines by Ritter reaction
Mikhailovskii, Alexander G.,Korchagin, Denis V.,Yusov, Aleksey S.,Gashkova, Oksana V.
, p. 1114 - 1119 (2017)
[Figure not available: see fulltext.] Cyanacetohydrazide, protected at the nitrogen atom of hydrazide group, underwent cyclocondensation by Ritter reaction with 3,3-dialkylbenzylcarbinols, forming 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines. The reagents
Synthesis of thiophenes, azoles and azines with potential biological activity by employing the versatile heterocyclic precursor N- benzoycyanoacetylhydrazine
Mohareb, Rafat M.,Ho, Jonathan Z.,Alfarouk, Fatma O.
, p. 1053 - 1066 (2008/03/11)
This research work is concerned with the use of N-benzoyl cyanoacetylhydrazine (3) in synthesizing several new heterocyclic compounds with potential biological activity, via its reaction with various chemical reagents. The synthesized derivatives have act
Synthesis and Crystal Structure of Piperidinium 2-Aryltriazolopyridinides and their Neutralization to 2-Aryltriazolopyridines
Hadi, Ali,Martin, Nazario,Seoane, Carlos,Soto, Jose L.,Albert, Armando,Cano, Felix
, p. 1229 - 1235 (2007/10/02)
A one step synthesis of novel piperidinium 2-aryltriazolopyridinides 6 from 2'-benzoyl-2-cyanoacetohydrazide (2) and α-substituted cinnamonitriles 3 is described.The reaction takes place by 6-exo-dig cyclization followed by an 5-exo-trig pro