16501-75-0Relevant articles and documents
N-Substituted cyanacetohydrazides in the synthesis of 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines by Ritter reaction
Mikhailovskii, Alexander G.,Korchagin, Denis V.,Yusov, Aleksey S.,Gashkova, Oksana V.
, p. 1114 - 1119 (2017)
[Figure not available: see fulltext.] Cyanacetohydrazide, protected at the nitrogen atom of hydrazide group, underwent cyclocondensation by Ritter reaction with 3,3-dialkylbenzylcarbinols, forming 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines. The reagents
Synthesis and Crystal Structure of Piperidinium 2-Aryltriazolopyridinides and their Neutralization to 2-Aryltriazolopyridines
Hadi, Ali,Martin, Nazario,Seoane, Carlos,Soto, Jose L.,Albert, Armando,Cano, Felix
, p. 1229 - 1235 (2007/10/02)
A one step synthesis of novel piperidinium 2-aryltriazolopyridinides 6 from 2'-benzoyl-2-cyanoacetohydrazide (2) and α-substituted cinnamonitriles 3 is described.The reaction takes place by 6-exo-dig cyclization followed by an 5-exo-trig pro